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J-GLOBAL ID：201902263449799077   Reference number：19A1861521

Development of monoclonal mouse antibodies that specifically recognize pancreatic polypeptide

膵臓ポリペプチドを特異的に認識するマウスモノクローナル抗体の開発

Author (17)： Hara Akemi (Department of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan) ,  Hara Akemi (Center for Therapeutic Innovation in Diabetes, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan) ,  Nakagawa Yuko (Laboratory of Developmental Biology & Metabolism, Institute for Molecular and Cellular Regulation, Gunma University, Gunma 371-8512, Japan) ,  Nakao Keiko (Department of Physiology, Faculty of Medicine, Saitama Medical University, Saitama 350-0495, Japan) ,  Tamaki Motoyuki (Diabetes Therapeutics and Research Center, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan) ,  Ikemoto Tetsuya (Department of Digestive and Transplant Surgery, Tokushima University, Tokushima 770-8503, Japan) ,  Shimada Mitsuo (Department of Digestive and Transplant Surgery, Tokushima University, Tokushima 770-8503, Japan) ,  Matsuhisa Munehide (Diabetes Therapeutics and Research Center, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan) ,  Mizukami Hiroki (Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, Aomori 036-8562, Japan) ,  Maruyama Nobuhiro (Immuno-Biological Laboratories Co., Ltd., Gunma 375-0005, Japan) ,  Watada Hirotaka (Department of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan) ,  Watada Hirotaka (Sportology Center, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan) ,  Watada Hirotaka (Center for Therapeutic Innovation in Diabetes, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan) ,  Watada Hirotaka (Center for Identification of Diabetic Therapeutic Targets, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan) ,  Fujitani Yoshio (Department of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan) ,  Fujitani Yoshio (Center for Therapeutic Innovation in Diabetes, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan) ,  Fujitani Yoshio (Laboratory of Developmental Biology & Metabolism, Institute for Molecular and Cellular Regulation, Gunma University, Gunma 371-8512, Japan)
Material： Endocrine Journal (Web)
Volume： 66  Issue： 5  Page： 459-468(J-STAGE)  Publication year： 2019 
JST Material Number： U1479A  ISSN： 1348-4540  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,...
Semi thesaurus term： *Antibodies, Monoclonal, Murine-Derived ,...

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Author keywords (5)： Islet ,  Pancreatic polypeptide (PP) ,  Peptide YY ,  Neuropeptide Y ,  Monoclonal antibody

JST classification (2)： Basic medicine on endocrine system  (GL01020Q) ,  Production and application of antigens,antibodies,complements  (ED04030W)

Reference (38)：

• 1 Larsson LI, Sundler F, Hakanson R, Pollock HG, Kimmel JR (1974) Localization of APP, a postulated new hormone, to a pancreatic endocrine cell type. Histochemistry 42: 377-382.
• 2 Larsson LI, Sundler F, Hakanson R (1975) Immunohistochemical localization of human pancreatic polypeptide (HPP) to a population of islet cells. Cell Tissue Res 156: 167-171.
• 3 Greider MH, Gersell DJ, Gingerich RL (1978) Ultrastructural localization of pancreatic polypeptide in the F cell of the dog pancreas. J Histochem Cytochem 26: 1103-1108.
• 4 Kimmel JR, Pollock HG, Chance RE, Johnson MG, Reeve JR Jr, et al. (1984) Pancreatic polypeptide from rat pancreas. Endocrinology 114: 1725-1731.
• 5 Holzer P, Reichmann F, Farzi A (2012) Neuropeptide Y, peptide YY and pancreatic polypeptide in the gut-brain axis. Neuropeptides 46: 261-274.

Terms in the title (4)： 膵臓ポリペプチド ,  マウス ,  モノクローナル抗体 ,  開発