Art

J-GLOBAL ID：201902263731695653   Reference number：19A1104672

Mechanism of Siponimod: Anti-Inflammatory and Neuroprotective Mode of Action

Siponimodの機構:抗炎症および神経保護作用機序【JST・京大機械翻訳】

Author (5)： Behrangi Newshan (Department of Anatomy II, Ludwig-Maximilians-University of Munich, 80336 Munich, Germany) ,  Behrangi Newshan (Department of Anatomy, University Medical Center, 39071 Rostock, Germany) ,  Fischbach Felix (Department of Anatomy II, Ludwig-Maximilians-University of Munich, 80336 Munich, Germany) ,  Kipp Markus (Department of Anatomy II, Ludwig-Maximilians-University of Munich, 80336 Munich, Germany) ,  Kipp Markus (Department of Anatomy, University Medical Center, 39071 Rostock, Germany)
Material： Cells (Web)
Volume： 8  Issue： 1  Page： 24  Publication year： 2019 
JST Material Number： U7155A  ISSN： 2073-4409  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Multiple sclerosis (MS) is a n...

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Thesaurus term： *anti-inflammatory action ,  interaction ,  lymphocyte ,  therapeutic planning ,  monocyte ,  human(primates) ,  multiple sclerosis ,  central nervous system ,  *inflammation
Semi thesaurus term： 免疫細胞 ,  病巣 ,  神経変性 ,  病理組織学 ,  若年成人 ,  *神経 ,  *神経保護 , 【Automatic Indexing@JST】

Author keywords (5)： multiple sclerosis ,  neurodegeneration ,  inflammation ,  siponimod ,  progressive

JST classification (2)： Congenital diseases,deformities in general.  (GD03010V) ,  Infectious diseases,parasitics diseases in general.  (GD01010H)

Reference (94)：

• Pirko, I. Gray matter involvement in multiple sclerosis. Neurology 2007, 68, 634-642.
• Lucchinetti, C.F. Inflammatory cortical demyelination in early multiple sclerosis. N. Engl. J. Med. 2011, 365, 2188-2197.
• Frischer, J.M. The relation between inflammation and neurodegeneration in multiple sclerosis brains. Brain 2009, 132, 1175-1189.
• Kutzelnigg, A. Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain 2005, 128, 2705-2712.
• Stys, P.K. Will the real multiple sclerosis please stand up? Nat. Rev. Neurosci. 2012, 13, 507-514.

Terms in the title (3)： 抗炎症 ,  神経 ,  作用機序