Art

J-GLOBAL ID：201902264305189176   Reference number：19A0253865

Altered Expression of Small Intestinal Drug Transporters and Hepatic Metabolic Enzymes in a Mouse Model of Familial Alzheimer’s Disease

家族性Alzheimer病のマウスモデルにおける小腸薬物輸送体と肝臓代謝酵素の発現変化【JST・京大機械翻訳】

Author (7)： Pan Yijun (Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Victoria, Australia) ,  Omori Kotaro (Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, Japan) ,  Ali Izna (UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, North Carolina, United States) ,  Tachikawa Masanori (Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, Japan) ,  Terasaki Tetsuya (Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University, Japan) ,  Brouwer Kim L. R. (UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, North Carolina, United States) ,  Nicolazzo Joseph A. (Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Victoria, Australia)
Material： Molecular Pharmaceutics
Volume： 15  Issue： 9  Page： 4073-4083  Publication year： 2018 
JST Material Number： W3686A  ISSN： 1543-8384  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Drug transporter expression an...

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Thesaurus term： *Alzheimer disease ,  hepatocyte ,  immunohistochemistry ,  *mouse(animal) ,  UDP glucuronosyltransferase ,  *small intestine ,  targeting ,  wild type ,  visualization ,  proteomics ,  lipid ,  transgenic mouse
Semi thesaurus term： 蛋白質発現 ,  *輸送体 ,  *代謝酵素 , 【Automatic Indexing@JST】

Author keywords (5)： Alzheimer’s disease ,  small intestine ,  liver ,  drug transporters ,  drug-metabolizing enzymes

JST classification (2)： Nervous system diseases  (GN03000O) ,  Basic neurology  (GN01020W)

Terms in the title (7)： 家族性Alzheimer病 ,  マウスモデル ,  小腸 ,  薬物輸送体 ,  肝臓 ,  代謝酵素 ,  発現