Art

J-GLOBAL ID：201902265430849635   Reference number：19A1210592

Leptomeningeal recurrence after long-term alectinib therapy for non-small cell lung cancer harboring an EML4-ALK fusion protein

EML4-ALK融合蛋白質を持つ非小細胞肺癌に対する長期アレクチニブ療法後の髄膜腫再発【JST・京大機械翻訳】

Author (11)： Kawamura Takahisa (Division of Thoracic Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan) ,  Murakami Haruyasu (Division of Thoracic Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan) ,  Kobayashi Haruki (Division of Thoracic Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan) ,  Nakashima Kazuhisa (Division of Thoracic Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan) ,  Omori Shota (Division of Thoracic Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan) ,  Wakuda Kazushige (Division of Thoracic Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan) ,  Ono Akira (Division of Thoracic Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan) ,  Kenmotsu Hirotsugu (Division of Thoracic Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan) ,  Naito Tateaki (Division of Thoracic Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan) ,  Endo Masahiro (Division of Diagnostic Radiology, Shizuoka Cancer Center Hospital, Shizuoka, Japan) ,  Takahashi Toshiaki (Division of Thoracic Oncology, Shizuoka Cancer Center Hospital, Shizuoka, Japan)
Material： Investigational New Drugs
Volume： 37  Issue： 1  Page： 184-187  Publication year： 2019 
JST Material Number： W4500A  ISSN： 1573-0646  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： The recent approval of anaplas...

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Thesaurus term： man ,  *fusion protein ,  *therapy ,  reorganization ,  human(primates) ,  *recurrence ,  case report ,  *non-small cell lung cancer ,  complication ,  drug therapy ,  molecular targeting drug
Semi thesaurus term： 未分化リンパ腫 ,  チロシンキナーゼ阻害剤 ,  完全寛解 ,  病巣 ,  軟膜転移 ,  阻害剤 ,  再配列 , 【Automatic Indexing@JST】

Author keywords (4)： Non-small cell lung cancer ,  Leptomeningeal metastases ,  Anaplastic lymphoma kinase inhibitor ,  Alectinib

JST classification (3)： Tumors(=neoplasms)of respiratory system  (GI04000G) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C)

Substance index (1)： Alectinib

Terms in the title (8)： EML4-ALK ,  融合蛋白質 ,  非小細胞肺癌 ,  長期 ,  アレクチニブ ,  療法 ,  髄膜腫 ,  再発