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J-GLOBAL ID：201902265658655066   Reference number：19A1908778

Total Biosynthesis of Antiangiogenic Agent (-)-Terpestacin by Artificial Reconstitution of the Biosynthetic Machinery in Aspergillus oryzae

Aspergillus oryzaeにおける生合成機構の人工再構成による抗血管新生剤(-)-テルペスタシンの全生合成【JST・京大機械翻訳】

Author (6)： Narita Koji (Division of Chemistry, Graduate School of Science, Hokkaido University, Japan) ,  Minami Atsushi (Division of Chemistry, Graduate School of Science, Hokkaido University, Japan) ,  Ozaki Taro (Division of Chemistry, Graduate School of Science, Hokkaido University, Japan) ,  Liu Chengwei (Division of Chemistry, Graduate School of Science, Hokkaido University, Japan) ,  Kodama Motoichiro (Faculty of Agriculture, Tottori University, Japan) ,  Oikawa Hideaki (Division of Chemistry, Graduate School of Science, Hokkaido University, Japan)
Material： Journal of Organic Chemistry  (J Org Chem)
Volume： 83  Issue： 13  Page： 7042-7048  Publication year： 2018 
JST Material Number： C0328A  ISSN： 0022-3263  CODEN： JOCEAH  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： The total biosynthesis of (-)-...

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Thesaurus term： *reconstitution ,  *biosynthesis ,  gene ,  hydroxy group ,  oxidase ,  *Aspergillus oryzae ,  synthase ,  catalyst ,  enolization ,  *angiogenesis inhibitor ,  chemical synthesis ,  Flavins ,  terpene synthase ,  heterologous expression ,  *microorganism ,  *Deuteromycetes ,  *Hyphomycetes ,  *Plectomycetes

JST classification (5)： Synthesis of drugs  (GV01030F) ,  Applications of enzymes  (EB09100B) ,  Monoterpenes,sesquiterpenes  (CF10022A) ,  Other natural substances of biological origin  (CF10090R) ,  Cyclization reaction,ring-opening reaction  (CF02050I)

Substance index (1)： Terpestacin

Terms in the title (6)： Aspergillus ,  生合成 ,  人工 ,  再構成 ,  抗血管新生剤 ,  テルペスタシン