Art

J-GLOBAL ID：201902266615459661   Reference number：19A0981753

Carbocisteine stimulated an increase in ciliary bend angle via a decrease in [Cl^-]_i in mouse airway cilia

カルボシステインはマウス気道繊毛における[Cl-]iの減少を介して繊毛屈曲角の増加を刺激する【JST・京大機械翻訳】

Author (14)： Ikeuchi Yukiko (Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan) ,  Ikeuchi Yukiko (Research Center for Drug Discovery and Pharmaceutical Development Science, Research Organization of Science and Technology, BKC, Ritsumeikan University, Kusatsu, Shiga, Japan) ,  Kogiso Haruka (Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan) ,  Kogiso Haruka (Research Center for Drug Discovery and Pharmaceutical Development Science, Research Organization of Science and Technology, BKC, Ritsumeikan University, Kusatsu, Shiga, Japan) ,  Hosogi Shigekuni (Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan) ,  Tanaka Saori (Laboratory of Pharmacotherapy, Osaka University of Pharmaceutical Sciences, Takatsuki, Japan) ,  Shimamoto Chikao (Laboratory of Pharmacotherapy, Osaka University of Pharmaceutical Sciences, Takatsuki, Japan) ,  Matsumura Hitoshi (Laboratory of Pharmacotherapy, Osaka University of Pharmaceutical Sciences, Takatsuki, Japan) ,  Inui Toshio (Research Center for Drug Discovery and Pharmaceutical Development Science, Research Organization of Science and Technology, BKC, Ritsumeikan University, Kusatsu, Shiga, Japan) ,  Inui Toshio (Saisei Mirai Clinics, Moriguchi, Japan) ,  Marunaka Yoshinori (Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan) ,  Marunaka Yoshinori (Research Center for Drug Discovery and Pharmaceutical Development Science, Research Organization of Science and Technology, BKC, Ritsumeikan University, Kusatsu, Shiga, Japan) ,  Marunaka Yoshinori (Research Institute for Clinical Physiology, Kyoto Industrial Health Association, Kyoto, Japan) ,  Nakahari Takashi (Research Center for Drug Discovery and Pharmaceutical Development Science, Research Organization of Science and Technology, BKC, Ritsumeikan University, Kusatsu, Shiga, Japan)
Material： Pfluegers Archiv
Volume： 471  Issue： 2  Page： 365-380  Publication year： 2019 
JST Material Number： H0787A  ISSN： 0031-6768  CODEN： PFLABK  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Carbocisteine (CCis), a mucoac...

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Thesaurus term： mucosa ,  *cilium ,  Ciliary Body ,  respiratory tract disease ,  Chloride Channels ,  *Mus musculus ,  *Chlorine ,  *air duct (respiration) ,  protein kinase A ,  cotransport ,  heartbeat ,  invasion ,  ciliary cell ,  Ion Transport ,  transportation ,  Biological Transport ,  transmembrane protein ,  ion transport(in vivo) ,  *Myomorpha ,  aliphatic amine ,  sulfide (organic) ,  aliphatic carboxylic acid ,  sulfur containing amino acid ,  primary amine
Semi thesaurus term： 阻害剤 , 【Automatic Indexing@JST】

Author keywords (4)： Airway cilia ,  Intracellular Cl- concentration ,  Ciliary beating angle ,  Inner dynein

JST classification (3)： Transport of cell membrane  (EF04020R) ,  Respiratory system in general  (EJ05010Z) ,  Cell physiology in general  (EF02010S)

Substance index (1)： Carbocysteine

Terms in the title (6)： カルボシステイン ,  マウス ,  気道 ,  繊毛 ,  屈曲角 ,  刺激