Art

J-GLOBAL ID：201902266936118869   Reference number：19A2607737

Conformational equilibrium defines the variable induction of the multidrug-binding transcriptional repressor QacR

立体配座平衡は多剤結合転写レプレッサーQacRの可変誘導を定義する【JST・京大機械翻訳】

Author (7)： Takeuchi Koh (Biomedicinal Information Research Center, National Institute of Advanced Industrial Science and Technology, 135-0064 Tokyo, Japan) ,  Takeuchi Koh (Molecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology, 135-0064 Tokyo, Japan) ,  Takeuchi Koh (Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency (JST), 135-0064 Tokyo, Japan) ,  Imai Misaki (Research and Development Department, Japan Biological Informatics Consortium, 135-0064 Tokyo, Japan) ,  Shimada Ichio (Biomedicinal Information Research Center, National Institute of Advanced Industrial Science and Technology, 135-0064 Tokyo, Japan) ,  Shimada Ichio (Molecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology, 135-0064 Tokyo, Japan) ,  Shimada Ichio (Graduate School of Pharmaceutical Sciences, The University of Tokyo, 113-0033 Tokyo, Japan)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 116  Issue： 40  Page： 19963-19972  Publication year： 2019 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： QacR, a multidrug-binding tran...

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Thesaurus term： gene ,  ligature ,  *steric conformation ,  *repressor ,  NMR ,  dysfunction ,  *conformational equilibrium ,  Staphylococcus aureus ,  multiple drug resistance
Semi thesaurus term： 転写調節 ,  輸送体 ,  起因菌 , 【Automatic Indexing@JST】

Author keywords (5)： multidrug resistance ,  transcription factor ,  structure ,  dynamics ,  NMR

JST classification (2)： Molecular structure  (EB03020Y) ,  Receptors on cell membrane  (EF04030C)

Terms in the title (6)： 立体配座平衡 ,  転写 ,  レプレッサー ,  可変 ,  誘導 ,  定義