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J-GLOBAL ID：201902267416803100   Reference number：19A0722943

Altered development of dopaminergic neurons differentiated from stem cells from human exfoliated deciduous teeth of a patient with Down syndrome

Down症候群患者のヒト剥離乳歯由来の幹細胞から分化したドーパミン作動性ニューロンの変化した発達【JST・京大機械翻訳】

Author (11)： Pham Thanh Thi Mai (Section of Oral Medicine for Child, Division of Oral Health, Growth & Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan) ,  Kato Hiroki (Section of Oral Medicine for Child, Division of Oral Health, Growth & Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan) ,  Yamaza Haruyoshi (Section of Oral Medicine for Child, Division of Oral Health, Growth & Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan) ,  Masuda Keiji (Section of Oral Medicine for Child, Division of Oral Health, Growth & Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan) ,  Hirofuji Yuta (Section of Oral Medicine for Child, Division of Oral Health, Growth & Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan) ,  Sato Hiroshi (Section of Oral Medicine for Child, Division of Oral Health, Growth & Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan) ,  Nguyen Huong Thi Nguyen (Section of Oral Medicine for Child, Division of Oral Health, Growth & Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan) ,  Han Xu (Section of Oral Medicine for Child, Division of Oral Health, Growth & Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan) ,  Zhang Yu (Section of Oral Medicine for Child, Division of Oral Health, Growth & Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan) ,  Taguchi Tomoaki (Department of Pediatric Surgery, Reproductive and Developmental Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Nonaka Kazuaki (Section of Oral Medicine for Child, Division of Oral Health, Growth & Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan)
Material： BMC Neurology (Web)
Volume： 18  Issue： 1  Page： 132  Publication year： 2018 
JST Material Number： U7438A  ISSN： 1471-2377  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Down syndrome (DS) is a common...

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Thesaurus term： pathophysiology ,  function analysis ,  chromosome ,  pathological state ,  versatility ,  *human ,  *stem cell ,  donor ,  morphology ,  statistical analysis ,  immunostaining ,  dysfunction ,  homeostasis ,  Nerve ,  catecholamine ,  primary amine

Author keywords (8)： Down syndrome ,  Dopamine ,  Human exfoliated deciduous teeth ,  SHED ,  Stem cells ,  Dopaminergic neurons ,  Differentiation ,  Dopamine secretion

JST classification (2)： Nervous system diseases  (GN03000O) ,  Basic neurology  (GN01020W)

Substance index (1)： Dopamine

Reference (35)：

• Prog Brain Res; Human and mouse model cognitive phenotypes in Down syndrome: implications for assessment; JO Edgin, GM Mason, G Spano, A Fernandez, L Nadel; 197; 2012; 123-151; 10.1016/B978-0-444-54299-1.00007-8; citation_id=CR1
• Wiley Interdiscip Rev Cogn Sci; Cognition in Down syndrome: a developmental cognitive neuroscience perspective; JO Edgin; 4; 3; 2013; 307-317; 10.1002/wcs.1221; citation_id=CR2
• Ment Retard Dev Disabil Res Rev; Education and children with Down syndrome: neuroscience, development, and intervention; DJ Fidler, L Nadel; 13; 3; 2007; 262-271; 10.1002/mrdd.20166; citation_id=CR3
• Lancet Neurol; Cognitive deficits and associated neurological complications in individuals with Down's syndrome; IT Lott, M Dierssen; 9; 6; 2010; 623-633; 10.1016/S1474-4422(10)70112-5; citation_id=CR4
• Am J Intellect Dev Disabil; Symptoms of attention-deficit/hyperactivity disorder in Down syndrome: effects of the dopamine receptor D4 gene; GM Mason, G Spano, J Edgin; 120; 1; 2015; 58-71; 10.1352/1944-7558-120.1.58; citation_id=CR5

Terms in the title (8)： Down症候群 ,  患者 ,  ヒト ,  乳歯 ,  幹細胞 ,  分化 ,  ドーパミン作動性ニューロン ,  発達