Art

J-GLOBAL ID：201902268344866965   Reference number：19A2156081

Screening of new therapeutic compounds for tuberous sclerosis complex

結節性硬化症に対する新しい治療薬の探索

Author (3)： YAMAGATA KANATO (東京都医学研総合研) ,  SHIMADA TADAYUKI (東京都医学研総合研) ,  SUGIURA HIROKO (東京都医学研総合研)
Material： てんかん治療研究振興財団研究年報  (Annual Report of the Japan Epilepsy Research Foundation)
Volume： 30  Page： 57-64  Publication year： Sep. 01, 2019 
JST Material Number： J1276A  ISSN： 0915-5902  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： hereditary disease ,...
Semi thesaurus term： Tuberous Sclerosis ,...

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JST classification (1)： Basic neurology  (GN01020W)

Reference (13)：

• Yamagata K, Sanders LK, Kaufmann WE, Yee W, Barnes CA, Nathans D, et al. rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein. J Biol Chem 1994 ; 269 : 16333-16339.
• Crino PB, Nathanson KL, Henske EP. The tuberous sclerosis complex. N Engl J Med 2006 ; 355 : 1345-1356.
• Krueger DA, Wilfong AA, Holland-Bouley K, Anderson AE, Agricola K, Tudor C, et al. Everolimus treatment of refractory epilepsy in tuberous sclerosis complex. Ann Neurol 2013 ; 74 : 679-687.
• Krueger DA, Sadhwani A, Byars AW, de Vries PJ, Franz DN, Whittemore VH, et al. Everolimus for treatment of tuberous sclerosis complex-associated neuropsychiatric disorders. Ann Clin Transl Neurol 2017 ; 4 : 877-887.
• Ehninger D, Han S, Shilyansky C, Zhou Y, Li W, Kwiatkowski DJ, et al. Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis. Nat Med 2008 ; 14 : 843-848.

Terms in the title (3)： 結節性硬化症 ,  治療薬 ,  探索