Art

J-GLOBAL ID：201902270876422424   Reference number：19A1861248

Cardiotoxicity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure through lactation in mice

マウスの授乳による2,3,7,8-テトラクロロジベンゾ-p-ダイオキシン曝露により誘導される心臓毒性

Author (5)： Fujisawa Nozomi (Laboratory of Environmental Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo) ,  Tohyama Chiharu (Laboratory of Environmental Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo) ,  Tohyama Chiharu (Faculty of Medicine, University of Tsukuba) ,  Yoshioka Wataru (Laboratory of Environmental Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo) ,  Yoshioka Wataru (Department of Public Health & Environmental Medicine, The Jikei University School of Medicine)
Material： Journal of Toxicological Sciences  (J Toxicol Sci)
Volume： 44  Issue： 7  Page： 505-513(J-STAGE)  Publication year： 2019 
JST Material Number： Z0265B  ISSN： 0388-1350  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： pollutant ,...
Semi thesaurus term： IL-1 beta ,...

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Author keywords (4)： 2378-Tetrachlorodibenzo-p-dioxin (TCDD) ,  Cardiotoxicity ,  Mouse ,  Lactational exposure

JST classification (2)： Toxicity of organic compounds  (GZ02030Y) ,  Basic medicine on cardiovascular system  (GJ01020K)

Substance index (2)： 2,3,7,8-TCDD ,  Endothelin-1

Reference (32)：

• Aragon, A.C., Kopf, P.G., Campen, M.J., Huwe, J.K. and Walker, M.K. (2008): In utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effects on fetal and adult cardiac gene expression and adult cardiac and renal morphology. Toxicol. Sci., 101, 321-330.
• Consonni, D., Pesatori, A.C., Zocchetti, C., Sindaco, R., D’Oro, L.C., Rubagotti, M. and Bertazzi, P.A. (2008): Mortality in a population exposed to dioxin after the Seveso, Italy, accident in 1976: 25 years of follow-up. Am. J. Epidemiol., 167, 847-858.
• Fujisawa, N., Nakayama, S.M., Ikenaka, Y. and Ishizuka, M. (2014): TCDD-induced chick cardiotoxicity is abolished by a selective cyclooxygenase-2 (COX-2) inhibitor NS398. Arch. Toxicol., 88, 1739-1748.
• Gaasch, W.H. and Zile, M.R. (2011): Left ventricular structural remodeling in health and disease: with special emphasis on volume, mass, and geometry. J. Am. Coll. Cardiol., 58, 1733-1740.
• Guo, Y.L., Lambert, G.H., Hsu, C.C. and Hsu, M.M. (2004): Yucheng: health effects of prenatal exposure to polychlorinated biphenyls and dibenzofurans. Int. Arch. Occup. Environ. Health, 77, 153-158.

Terms in the title (6)： マウス ,  授乳 ,  ダイオキシン ,  曝露 ,  誘導 ,  心臓毒性