Art

J-GLOBAL ID：201902271341961184   Reference number：19A1650758

Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases

短鎖脂肪酸(SCFAs)媒介腸上皮および免疫調節と炎症性腸疾患に対するその関連性【JST・京大機械翻訳】

Author (11)： Parada Venegas Daniela (Laboratory of Innate Immunity, Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile) ,  Parada Venegas Daniela (Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands) ,  De la Fuente Marjorie K. (Laboratory of Innate Immunity, Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile) ,  Landskron Glauben (Laboratory of Innate Immunity, Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile) ,  Gonzalez Maria Julieta (Program of Cell and Molecular Biology, Faculty of Medicine, Institute of Biomedical Sciences, Universidad de Chile, Santiago, Chile) ,  Quera Rodrigo (Inflammatory Bowel Diseases Program, Department of Gastroenterology, Clinica Las Condes, Santiago, Chile) ,  Dijkstra Gerard (Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands) ,  Harmsen Hermie J. M. (Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands) ,  Faber Klaas Nico (Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands) ,  Faber Klaas Nico (Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands) ,  Hermoso Marcela A. (Laboratory of Innate Immunity, Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile)
Material： Frontiers in Immunology (Web)
Volume： 10  Page： 277  Publication year： 2019 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Ulcerative colitis (UC) and Cr...

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Thesaurus term： transgenic mouse ,  probiotics ,  heredity ,  intestinal mucosa ,  interaction ,  therapy ,  metabolite ,  *bacterium ,  metabolic error ,  human(primates) ,  life style
Semi thesaurus term： GPR43 ,  GPR41 ,  MCT1 ,  ブチラート ,  常在菌叢ゲノム , 【Automatic Indexing@JST】

Author keywords (6)： SCFAs ,  IBD ,  immune cells ,  IECs ,  intestinal mucosa ,  dysbiosis

JST classification (1)： Immunological reaction in general  (ED03010T)

Reference (151)：

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• De Souza HSP, Fiocchi C. Immunopathogenesis of IBD: current state of the art. Nat Rev Gastroenterol Hepatol. (2016) 13:13-27. doi: 10.1038/nrgastro.2015.186
• Sommer F, Bäckhed F. The gut microbiota-masters of host development and physiology. Nat Rev Microbiol. (2013) 11:227-38. doi: 10.1038/nrmicro2974
• Thorburn AN, Macia L, Mackay CR. Diet, metabolites, and “Western-Lifestyle” inflammatory diseases. Immunity. (2014) 40:833-842. doi: 10.1016/j.immuni.2014.05.014

Terms in the title (5)： 短鎖脂肪酸 ,  腸上皮 ,  免疫調節 ,  炎症性腸疾患 ,  関連性