Art

J-GLOBAL ID：201902272279299198   Reference number：19A2299364

Interactions of an Anti-Sickling Drug with Hemoglobin in Red Blood Cells from a Patient with Sickle Cell Anemia

鎌状赤血球Anemia患者由来赤血球における抗鎌状薬とヘモグロビンとの相互作用【JST・京大機械翻訳】

Author (10)： Strader Michael Brad (Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Maryland, United States) ,  Liang Hongying (Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Maryland, United States) ,  Meng Fantao (Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Maryland, United States) ,  Harper Julia (Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Maryland, United States) ,  Ostrowski David A. (Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Maryland, United States) ,  Henry Eric R. (Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Maryland, United States) ,  Shet Arun S. (Sickle Cell Branch, National Heart Lung and Blood Institute, National Institutes of Health, Maryland, United States) ,  Eaton William A. (Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Maryland, United States) ,  Thein Swee L. (Sickle Cell Branch, National Heart Lung and Blood Institute, National Institutes of Health, Maryland, United States) ,  Alayash Abdu I. (Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Maryland, United States)
Material： Bioconjugate Chemistry  (Bioconj Chem)
Volume： 30  Issue： 3  Page： 568-571  Publication year： 2019 
JST Material Number： W0169A  ISSN： 1043-1802  CODEN： BCCHES  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： The pathophysiology associated...

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Thesaurus term： Polymerization ,  complex (substance) ,  optimization ,  therapy ,  human ,  Hemolysis ,  *sickle cell ,  *hemoglobin ,  pathological state ,  steric conformation ,  in vitro experiment ,  oxygenation ,  oral administration ,  mass spectrometry ,  *interaction ,  modification

JST classification (1)： Proteins and peptides in general  (EB03010N)

Terms in the title (5)： 鎌状赤血球 ,  患者 ,  赤血球 ,  ヘモグロビン ,  相互作用