Art

J-GLOBAL ID：201902272508275108   Reference number：19A2895971

Genetic modifiers of rodent animal models: the role in cataractogenesis

げっ歯類動物モデルの遺伝的修飾因子:白内障発生における役割

Author (4)： Wada Kenta (Faculty of Bioindustry, Tokyo University of Agriculture, 196 Yasaka, Abashiri, Hokkaido 099-2493, Japan) ,  Wada Kenta (Mammalian Genetics Project, Department of Genome Medicine, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan) ,  Yasuda Shumpei P. (Mammalian Genetics Project, Department of Genome Medicine, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan) ,  Kikkawa Yoshiaki (Mammalian Genetics Project, Department of Genome Medicine, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan)
Material： Experimental Animals  (実験動物ニュース)
Volume： 68  Issue： 4  Page： 397-406(J-STAGE)  Publication year： 2019 
JST Material Number： Z0755A  ISSN： 1341-1357  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： rat ,...
Semi thesaurus term： *genetic modifier ,...

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Author keywords (5)： cataract ,  genetic modifier ,  lens transparency ,  mouse model ,  rat model

JST classification (1)： Basic ophthalmology  (GP01020C)

Reference (72)：

• 1. Andley U.P. 2008. The lens epithelium: focus on the expression and function of the alpha-crystallin chaperones. Int. J. Biochem. Cell Biol. 40: 317-323.
• 2. Asbell P.A., Dualan I., Mindel J., Brocks D., Ahmad M. and Epstein S. 2005. Age-related cataract. Lancet 365: 599-609.
• 3. Bassnett S., Wilmarth P.A. and David L.L. 2009. The membrane proteome of the mouse lens fiber cell. Mol. Vis. 15: 2448-2463.
• 4. Bayés M., Giordano M., Balcells S., Grinberg D., Vilageliu L., Martínez I., Ayuso C., Benítez J., Ramos-Arroyo M.A., Chivelet P., Solans T., Valverde D., Amselem S., Goossens M., Baiget M., Gonzàlez R.D. and Besmond C. 1995. Homozygous tandem duplication within the gene encoding the β-subunit of rod phosphodiesterase as a cause for autosomal recessive retinitis pigmentosa. Hum. Mutat. 5: 228-234.
• 5. Berthoud V.M., and Beyer E.C. 2009. Oxidative stress, lens gap junctions, and cataracts. Antioxid. Redox Signal. 11: 339-353.

Terms in the title (5)： げっ歯類動物 ,  モデル ,  遺伝的修飾因子 ,  白内障 ,  役割