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J-GLOBAL ID：201902272756058231   Reference number：19A2403832

The RNA-binding protein Mex-3B plays critical roles in the development of steroid-resistant neutrophilic airway inflammation

RNA結合蛋白質MEX-3Bはステロイド耐性好中球気道炎症の発生において重要な役割を果たす【JST・京大機械翻訳】

Author (9)： Yamazumi Yusuke (Laboratory of Molecular and Genetic Information, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan) ,  Sasaki Oh (Department of Allergy and Rheumatology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan) ,  Suyama-Fuchino Saki (Laboratory of Molecular and Genetic Information, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan) ,  Kohu Kazuyoshi (Laboratory of Molecular and Genetic Information, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan) ,  Kamoshida Yuki (Laboratory of Molecular and Genetic Information, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan) ,  Harada Hiroaki (Department of Allergy and Rheumatology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan) ,  Fujio Keishi (Department of Allergy and Rheumatology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan) ,  Oda Takeaki (Laboratory of Molecular and Genetic Information, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan) ,  Akiyama Tetsu (Laboratory of Molecular and Genetic Information, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 519  Issue： 2  Page： 220-226  Publication year： 2019 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： While most asthma can be treat...

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Thesaurus term： asthma ,  therapy ,  human ,  United Mexican States ,  *steroid ,  chemotaxis ,  antibody ,  *air duct (respiration) ,  *Neutrophils ,  *Inflammation ,  chemokine ,  Mus musculus ,  Neutrophil Infiltration ,  *steroid resistance ,  Myomorpha
Semi thesaurus term： 重症喘息 ,  *気道炎症 , 【Automatic Indexing@JST】

Author keywords (6)： Severe asthma ,  Neutrophil ,  Mex-3B ,  CXCL2 ,  Antibody therapeutics ,  Nucleic acid therapeutics

JST classification (2)： Function of cell components  (EF03060C) ,  Immunologic diseases,allergic diseases in general.  (GD04010C)

Terms in the title (5)： RNA結合蛋白質 ,  ステロイド耐性 ,  好中球 ,  気道炎症 ,  役割