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J-GLOBAL ID：201902273023120290   Reference number：19A0963389

Identification of an Essential Cytoplasmic Region of Interleukin-7 Receptor α Subunit in B-Cell Development

B細胞発生におけるインターロイキン7受容体αサブユニットの必須細胞質領域の同定【JST・京大機械翻訳】

Author (7)： Kasai Hirotake (Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA) ,  Kuwabara Taku (Department of Molecular Immunology, Toho University School of Medicine, Tokyo 143-8540, Japan) ,  Matsui Yukihide (Department of Molecular Immunology, Toho University School of Medicine, Tokyo 143-8540, Japan) ,  Matsui Yukihide (Toho University Graduate School of Medicine, Tokyo 143-8540, Japan) ,  Matsui Yukihide (Department of Urology, Toho University Omori Medical Center, Tokyo 143-8541, Japan) ,  Nakajima Koichi (Department of Urology, Toho University Omori Medical Center, Tokyo 143-8541, Japan) ,  Kondo Motonari (Department of Molecular Immunology, Toho University School of Medicine, Tokyo 143-8540, Japan)
Material： International Journal of Molecular Sciences (Web)  (Int J Mol Sci (Web))
Volume： 19  Issue： 9  Page： 2522  Publication year： 2018 
JST Material Number： U7038A  ISSN： 1422-0067  CODEN： IJMCFK  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Interleukin-7 (IL-7) is essent...

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Thesaurus term： lymphocyte ,  *receptor ,  wild type ,  phosphorylation ,  cellular signal transduction ,  *interleukin 7 ,  *interleukin ,  deletion mutation ,  *cytoplasm ,  *subunit ,  amino acid ,  in vitro experiment ,  myeloid cell
Semi thesaurus term： IL7受容体 ,  造血前駆細胞 , 【Automatic Indexing@JST】

Author keywords (4)： interleukin-7 ,  interleukin-7 receptor ,  B-cell development ,  signal transducer and activator of transcription 5

JST classification (5)： Cell physiology in general  (EF02010S) ,  Influence on animals  (EE05040R) ,  Tumor immunity  (ED03040A) ,  Experimental treatment for tumors  (GE02040Y) ,  Immunotherapy for tumors  (GE03035B)

Reference (33)：

• Hofmeister, R.; Khaled, A.R.; Benbernou, N.; Rajnavolgyi, E.; Muegge, K.; Durum, S.K. Interleukin-7: Physiological roles and mechanisms of action. Cytokine Growth Factor Rev. 1999, 10, 41-60.
• Ceredig, R.; Rolink, A.G. The key role of IL-7 in lymphopoiesis. Semin. Immunol. 2012, 24, 159-164.
• Sugamura, K.; Asao, H.; Kondo, M.; Tanaka, N.; Ishii, N.; Ohbo, K.; Nakamura, M.; Takeshita, T. The interleukin-2 receptor gamma chain: Its role in the multiple cytokine receptor complexes and T cell development in XSCID. Annu. Rev. Immunol. 1996, 14, 179-205.
• Leonard, W.J. The molecular basis of X-linked severe combined immunodeficiency: Defective cytokine receptor signaling. Annu. Rev. Med. 1996, 47, 229-239.
• Rochman, Y.; Spolski, R.; Leonard, W.J. New insights into the regulation of T cells by γc family cytokines. Nat. Rev. Immunol. 2009, 9, 480-490.

Terms in the title (4)： B細胞 ,  インターロイキン7受容体αサブユニット ,  細胞質 ,  同定