Art

J-GLOBAL ID：201902273310240518   Reference number：19A1584886

Serum and nutrient deprivation increase autophagic flux in intervertebral disc annulus fibrosus cells: an in vitro experimental study

血清および栄養素欠乏は椎間板線維輪細胞における自食性フラックスを増加させる:in vitro実験的研究【JST・京大機械翻訳】

Author (18)： Yurube Takashi (Ferguson Laboratory for Orthopaedic and Spine Research, Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA) ,  Yurube Takashi (Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Buchser William J. (Damage Associated Molecular Pattern Molecule Laboratory, Department of Surgery, Hillman Cancer Center, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA) ,  Moon Hong Joo (Ferguson Laboratory for Orthopaedic and Spine Research, Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA) ,  Moon Hong Joo (Department of Neurosurgery, Guro Hospital, Korea University College of Medicine, Seoul, Korea) ,  Hartman Robert A. (Ferguson Laboratory for Orthopaedic and Spine Research, Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA) ,  Hartman Robert A. (Department of Physical Medicine and Rehabilitation, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA) ,  Takayama Koji (Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Takayama Koji (Department of Orthopaedic Surgery, Stem Cell Research Center, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA) ,  Kawakami Yohei (Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Kawakami Yohei (Department of Orthopaedic Surgery, Stem Cell Research Center, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA) ,  Nishida Kotaro (Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Kurosaka Masahiro (Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Vo Nam V. (Ferguson Laboratory for Orthopaedic and Spine Research, Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA) ,  Kang James D. (Ferguson Laboratory for Orthopaedic and Spine Research, Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA) ,  Lotze Michael T. (Damage Associated Molecular Pattern Molecule Laboratory, Department of Surgery, Hillman Cancer Center, University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA) ,  Sowa Gwendolyn A. (Ferguson Laboratory for Orthopaedic and Spine Research, Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA) ,  Sowa Gwendolyn A. (Department of Physical Medicine and Rehabilitation, University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, PA, USA)
Material： European Spine Journal
Volume： 28  Issue： 5  Page： 993-1004  Publication year： 2019 
JST Material Number： W4352A  ISSN： 0940-6719  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： The loss of nutrient supply is...

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Thesaurus term： Apoptosis ,  Cell Proliferation ,  *Serum ,  circular plate ,  Oxygen ,  *intervertebral disk ,  senile change ,  Western blotting ,  time dependence ,  *nutrient ,  Autophagy ,  *nutrient deficiency ,  substrate (biochemistry) ,  p62 ,  LC3 ,  *Cartilage ,  bioassay

Author keywords (6)： Intervertebral disc ,  Annulus fibrosus (AF) cells ,  Serum and nutrient deprivation ,  Autophagy ,  Apoptosis ,  Senescence

JST classification (5)： Musculoskeletal diseases  (GG03000T) ,  Clinical dermatology in general  (GF01030J) ,  Surgical treatment for musculoskeletal diseases  (GG05030O) ,  Occupational health,industorial accidents  (GB05000S) ,  Clinical medicine on musculoskeletal system in general  (GG01030M)

Terms in the title (8)： 血清 ,  栄養素欠乏 ,  椎間板 ,  線維輪 ,  細胞 ,  食性 ,  フラックス ,  実験的研究