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J-GLOBAL ID：201902273449732136   Reference number：19A1789163

Synthesis and characterization of novel radiofluorinated probes for positron emission tomography imaging of monoamine oxidase B

モノアミンオキシダーゼBの陽電子放出断層撮影イメージングのための新しい放射性フッ素化プローブの合成と特性化【JST・京大機械翻訳】

Author (9)： Yoshimoto Mitsuyoshi (Department of Biofunctional Analysis, Osaka University of Pharmaceutical Sciences, Takatsuki, Japan) ,  Yoshimoto Mitsuyoshi (Division of Functional Imaging, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Japan) ,  Hirata Masahiko (Department of Biofunctional Analysis, Osaka University of Pharmaceutical Sciences, Takatsuki, Japan) ,  Kagawa Shinya (Department of Biofunctional Analysis, Osaka University of Pharmaceutical Sciences, Takatsuki, Japan) ,  Kagawa Shinya (Division of PET Imaging, Shiga Medical Center Research Institute, Moriyama, Japan) ,  Magata Yasuhiro (Department of Nuclear Medicine and Diagnostic Imaging, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Magata Yasuhiro (Department of Molecular Imaging, Institute for Medical Photonics Research, Preeminent Medial Photonics Education and Research Center, Hamamatsu University School of Medicine, Hamamatsu, Japan) ,  Ohmomo Yoshiro (Department of Biofunctional Analysis, Osaka University of Pharmaceutical Sciences, Takatsuki, Japan) ,  Temma Takashi (Department of Biofunctional Analysis, Osaka University of Pharmaceutical Sciences, Takatsuki, Japan)
Material： Journal of Labelled Compounds and Radiopharmaceuticals  (Journal of Labelled Compounds & Radiopharmaceuticals)
Volume： 62  Issue： 9  Page： 580-587  Publication year： 2019 
JST Material Number： B0864A  ISSN： 0362-4803  CODEN： JLCRD  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Monoamine oxidase B (MAO-B), p...

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Thesaurus term： *PET(tomography) ,  *fluorination ,  biodistribution ,  *characterization ,  *probe ,  high speed ,  electrophilic reaction ,  in vitro experiment ,  *monoamine oxidase ,  pretreatment ,  *image processing ,  purity
Semi thesaurus term： ddYマウス ,  イメージングプローブ ,  阻害剤 , 【Automatic Indexing@JST】

Author keywords (7)： MAO ,  MAO-B ,  MD-230254 ,  monoamine oxidase ,  positron emission tomography ,  PET ,  SPECT

JST classification (2)： Labeled compounds  (CB10050N) ,  Aromatic monocyclic amine,imine,quaternary ammonium,immonium compounds  (CF05050D)

Terms in the title (7)： モノアミンオキシダーゼB ,  陽電子放出断層撮影 ,  イメージング ,  放射性 ,  フッ素化 ,  プローブ ,  特性化