Art

J-GLOBAL ID：201902274833431063   Reference number：19A1417360

Activation of protein kinase C accelerates murine osteoclastogenesis partly via transactivation of RANK gene through functional AP-1 responsive element in RANK gene promoter

蛋白質キナーゼCの活性化はRANK遺伝子プロモーターにおける機能的AP-1応答エレメントを介してRANK遺伝子のトランス活性化を介して部分的にマウス破骨細胞形成を促進する【JST・京大機械翻訳】

Author (8)： Kitazawa Riko (Department of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime, 791-0295, Japan) ,  Kitazawa Riko (Division of Diagnostic Molecular Pathology, Kobe University Graduate School of Medicine, Kusunoki-cho 7-5-1, Kobe, 650-0017, Japan) ,  Kitazawa Riko (Division of Diagnostic Pathology, Ehime University Hospital, Shitsukawa, Toon City, Ehime, 791-0295, Japan) ,  Kinto-Shibahara Satomi (Division of Diagnostic Molecular Pathology, Kobe University Graduate School of Medicine, Kusunoki-cho 7-5-1, Kobe, 650-0017, Japan) ,  Haraguchi Ryuma (Department of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime, 791-0295, Japan) ,  Kohara Yukihiro (Department of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime, 791-0295, Japan) ,  Kitazawa Sohei (Department of Molecular Pathology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime, 791-0295, Japan) ,  Kitazawa Sohei (Division of Diagnostic Molecular Pathology, Kobe University Graduate School of Medicine, Kusunoki-cho 7-5-1, Kobe, 650-0017, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 515  Issue： 2  Page： 268-274  Publication year： 2019 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Receptor activator of NF-κB (R...

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Thesaurus term： *AP-1 transcription factor ,  DNA ,  transfection ,  oligonucleotide ,  siRNA ,  monocyte ,  *promoter(genetics) ,  NF-kappaB ,  macrophage ,  binding site ,  *mouse(animal) ,  *osteoclast
Semi thesaurus term： プロモーター活性 ,  阻害剤 ,  *NF-κB活性化受容体 , 【Automatic Indexing@JST】

Author keywords (4)： CSF-1 ,  Fos ,  Osteoclasts ,  RANK

JST classification (3)： Skeletal system  (EJ10030R) ,  Gene expression  (EC02040Q) ,  Function of cell components  (EF03060C)

Terms in the title (11)： 蛋白質キナーゼC ,  活性化 ,  RANK ,  遺伝子プロモーター ,  AP-1 ,  応答エレメント ,  遺伝子 ,  トランス活性化 ,  マウス ,  破骨細胞形成 ,  促進