Art

J-GLOBAL ID：201902275907509777   Reference number：19A0344498

Changes in the sclerostin productivity of alveolar bone osteocytes due to mechanical stress changes

メカニカルストレスの変動に伴う歯槽骨骨細胞のsclerostin産生能の変化

Author (5)： KOMAGATA KANAKO (朝日大 歯 口腔構造機能発育学 歯科矯正学分野) ,  FUJIWARA ATSUSHI (朝日大 歯 口腔構造機能発育学 歯科矯正学分野) ,  WATANABE RYUTA (朝日大 歯 口腔構造機能発育学 口腔解剖学分野) ,  EJIRI SADAKAZU (朝日大 歯 口腔構造機能発育学 口腔解剖学分野) ,  KITAI NORIYUKI (朝日大 歯 口腔構造機能発育学 歯科矯正学分野)
Material： 岐阜歯科学会雑誌(Web)  (Journal of Gifu Dental Society (Web))
Volume： 45  Issue： 2  Page： 97-105 (WEB ONLY)  Publication year： Oct. 2018 
JST Material Number： U1081A  ISSN： 2433-0191  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： experimental disease ,...
Semi thesaurus term： mu CT ,...

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JST classification (2)： Basic dentistry(= odontology)  (GT01020O) ,  Cell physiology in general  (EF02010S)

Reference (17)：

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• Brunkow ME, Gardner JC, Van Ness J, Paeper BW, Kovacevich BR, Proll S, Skonier JE, Zhao L, Sabo PJ, Fu Y, Alisch RS, Gillett L, Colbert T, Tacconi P, Galas D, Hamersma H, Beighton P and Mulligan J. Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein. Am J Hum Genet. 2001; 68: 577-589.
• Winkler DG, Sutherland MK, Geoghegan JC, Yu C, Hayes T, Skonier JE, Shpektor D, Jonas M, Kovacevich BR, Staehling-Hampton K, Appleby M, Brunkow ME and Latham JA. Osteocyte control of bone formation via sclerostin, a novel BMP antagonist. Embo J. 2003; 22: 6267-6276.
• van Bezooijen RL, Roelen BA, Visser A, van der Wee-Pals L, de Wilt E, Karperien M, Hamersma H, Papapoul os SE, ten Dijke P and Lowik CW. Sclerostin is an osteocyte-expressed negativeregulator of bone formation, but not a classical BMP antagonist. J Exp Med. 2004; 199: 805-814.

Terms in the title (4)： メカニカルストレス ,  歯槽骨 ,  骨細胞 ,  能