Art

J-GLOBAL ID：201902276104371372   Reference number：19A2655835

CSF1R Ligands IL-34 and CSF1 Are Differentially Required for Microglia Development and Maintenance in White and Gray Matter Brain Regions

CSF1RリガンドIL-34およびCSF1は白色および灰白質脳領域におけるミクログリア発生および維持に特異的に必要である【JST・京大機械翻訳】

Author (5)： Easley-Neal Courtney (Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA, United States) ,  Foreman Oded (Department of Pathology, Genentech, Inc., South San Francisco, CA, United States) ,  Sharma Neeraj (Department of Pathology, Genentech, Inc., South San Francisco, CA, United States) ,  Zarrin Ali A. (Department of Immunology, Genentech, Inc., South San Francisco, CA, United States) ,  Weimer Robby M (Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA, United States)
Material： Frontiers in Immunology (Web)
Volume： 10  Page： 2199  Publication year： 2019 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Microglia are specialized brai...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=19A2655835&from=J-GLOBAL&jstjournalNo=U7074A") }}

Thesaurus term： administration(biology) ,  *M-CSF ,  receptor ,  *grey matter ,  receptor tyrosine kinase ,  *microglia ,  CSF ,  homeostasis ,  macrophage
Semi thesaurus term： 神経変性 ,  出生 ,  差次的遺伝子発現 ,  脳領域 ,  *リガンド , 【Automatic Indexing@JST】

Author keywords (5)： Csf1r ,  Csf1 ,  IL-34 ,  microglia ,  CNS

JST classification (2)： Basic neurology  (GN01020W) ,  Cell physiology in general  (EF02010S)

Reference (54)：

• Ransohoff RM, El Khoury J. Microglia in health and disease. Cold Spring Harb Perspect Biol. (2015) 8:a020560. doi: 10.1101/cshperspect.a020560
• Tay TL, Savage JC, Hui CW, Bisht K, Tremblay MÈ. Microglia across the lifespan: from origin to function in brain development, plasticity and cognition. J Physiol. (2016) 595:1929-45. doi: 10.1113/JP272134
• Hanisch UK, Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci. (2007) 10:1387-94. doi: 10.1038/nn1997
• Prinz M, Priller J. Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease. Nat Rev Neurosci. (2014) 15:300-12. doi: 10.1038/nrn3722
• Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science. (2010) 330:841-5. doi: 10.1126/science.1194637

Terms in the title (7)： リガンド ,  IL-34 ,  CSF1 ,  白色 ,  灰白質 ,  脳領域 ,  ミクログリア