Art

J-GLOBAL ID：201902276900013537   Reference number：19A0734403

Hypoxia promotes the migration and invasion of human hepatocarcinoma cells through the HIF-1α-IL-8-Akt axis

低酸素はHIF-1α-IL-8-Akt軸を介してヒト肝癌細胞の移動と浸潤を促進する【JST・京大機械翻訳】

Author (9)： Fei Maoyun (Department of General Surgery, The First People’s Hospital of Huzhou, Huzhou, People’s Republic of China) ,  Guan Jianming (Department of Ultrasound, The First People’s Hospital of Huzhou, Huzhou, People’s Republic of China) ,  Xue Tao (Central Laboratory, The First People’s Hospital of Huzhou, Huzhou, People’s Republic of China) ,  Qin Lianjin (Department of General Surgery, The First People’s Hospital of Huzhou, Huzhou, People’s Republic of China) ,  Tang Chengwu (Department of Hepatobiliary Pancreatic Surgery, The First People’s Hospital of Huzhou, Huzhou, People’s Republic of China) ,  Cui Ge (Department of General Surgery, The First People’s Hospital of Huzhou, Huzhou, People’s Republic of China) ,  Wang Yao (Department of General Surgery, The First People’s Hospital of Huzhou, Huzhou, People’s Republic of China) ,  Gong Hui (Central Laboratory, The First People’s Hospital of Huzhou, Huzhou, People’s Republic of China) ,  Feng Wenming (Department of Hepatobiliary Pancreatic Surgery, The First People’s Hospital of Huzhou, Huzhou, People’s Republic of China)
Material： Cellular & Molecular Biology Letters (Web)
Volume： 23  Issue： 1  Page： 46  Publication year： 2018 
JST Material Number： U7375A  ISSN： 1689-1392  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Hepatocellular carcinoma (HCC)...

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Thesaurus term： *human(primates) ,  cell migration ,  *interleukin 8 ,  chemokine ,  metastasis ,  gene silencing ,  *oxygen deficiency ,  drug therapy ,  *immersional wetting ,  hepatoma
Semi thesaurus term： 遊走 ,  伝達経路 ,  阻害剤 ,  遺伝子ノックダウン法 ,  *Akt/蛋白質キナーゼB , 【Automatic Indexing@JST】

Author keywords (5)： Hepatocarcinoma ,  Hypoxia ,  HIF-1α ,  IL-8 ,  Akt pathway

JST classification (2)： Cell physiology in general  (EF02010S) ,  Gene expression  (EC02040Q)

Reference (31)：

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• Lancet; Hepatocellular carcinoma; A Forner, JM Llovet, J Bruix; 379; 9822; 2012; 1245-1255; 10.1016/S0140-6736(11)61347-0; citation_id=CR2
• Ann Surg; Early and late recurrence after liver resection for hepatocellular carcinoma: prognostic and therapeutic implications; N Portolani, A Coniglio, S Ghidoni, M Giovanelli, A Benetti, GAM Tiberio; 243; 2; 2006; 229-235; 10.1097/01.sla.0000197706.21803.a1; citation_id=CR3
• Hepatology; Molecular mechanisms of hepatocellular carcinoma; RN Aravalli, CJ Steer, ENK Cressman; 48; 6; 2008; 2047-2063; 10.1002/hep.22580; citation_id=CR4
• Curr Opin Genet Dev; Hypoxia inducible factors: central regulators of the tumor phenotype; JD Gordan, MC Simon; 17; 1; 2007; 71-77; 10.1016/j.gde.2006.12.006; citation_id=CR5

Terms in the title (8)： 低酸素 ,  HIF-1α ,  IL-8 ,  Akt ,  ヒト ,  肝癌細胞 ,  浸潤 ,  促進