Art

J-GLOBAL ID：201902277120090626   Reference number：19A0447121

Synthesis of gentianine N-oxide by enzymatic hydrolysis of swertiamarin in the presence of hydroxylamine and reaction pathway to gentianine and gentianol

ヒドロキシルアミンの存在下でのスウェルチアマリンの酵素加水分解によるゲンチアニンN-オキシドの合成およびゲンチアニンとゲンチアノールへの反応経路【JST・京大機械翻訳】

Author (7)： Fujii Mikio (School of Pharmacy, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara, Tochigi 324-8501, Japan) ,  Kuramochi Taiki (School of Pharmacy, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara, Tochigi 324-8501, Japan) ,  Nakakuki Yuhi (School of Pharmacy, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara, Tochigi 324-8501, Japan) ,  Hatazawa Rina (School of Pharmacy, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara, Tochigi 324-8501, Japan) ,  Konno Kiju (School of Pharmacy, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara, Tochigi 324-8501, Japan) ,  Munakata Tatsuo (School of Pharmacy, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara, Tochigi 324-8501, Japan) ,  Hirai Yasuaki (Faculty of Arts and Sciences at Fujiyoshida, Showa University, 4562 Kamiyoshida, Fujiyoshida, Yamanashi 403-0005, Japan)
Material： Tetrahedron Letters  (Tetrahedron Lett)
Volume： 60  Issue： 10  Page： 721-725  Publication year： 2019 
JST Material Number： E0366A  ISSN： 0040-4039  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Gentianine is a metabolite of ...

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Thesaurus term： *reaction path ,  natural material ,  herb ,  hypoglycemic action ,  *oxide ,  anti-inflammatory action ,  glucosidase ,  *Hydrolysis ,  metabolite ,  *hydroxylamine ,  beta-Glucosidase ,  biological activity ,  acetal ,  lactone ,  vinyl compound ,  pyranoside ,  glucoside
Semi thesaurus term： Swertia , 【Automatic Indexing@JST】

Author keywords (4)： Gentiopicroside ,  Swertiamarin ,  β-Glucosidase-catalyzed hydrolysis ,  Genatianine N-oxide

JST classification (2)： Eight or more-membered heterocyclic compounds  (CF07120T) ,  Other 5-membered rings with two or more hetero atoms  (CF07085F)

Substance index (2)： Gentiopicroside ,  Swertiamarin

Terms in the title (5)： ヒドロキシルアミン ,  スウェルチアマリン ,  酵素加水分解 ,  N-オキシド ,  反応経路