Art
J-GLOBAL ID：201902279184159413   Reference number：19A1301490

Decrease of endotoxin activity in solutions containing a chelating agent and a detergent (Mechanism of Low Endotoxin Recovery)

キレート剤と界面活性剤によるエンドトキシンの活性低下 (Low Endotoxin Recoveryの機序)
Author (1)：
TSUCHIYA MASAKAZU

About TSUCHIYA MASAKAZU

(Charles River, Microbial Solutions)

About Charles River, Microbial Solutions


Material：
エンドトキシン・自然免疫研究(Web)

About エンドトキシン・自然免疫研究(Web)


Volume： 21  Page： 23-25(J-STAGE)  Publication year： 2018 
JST Material Number： U1552A  ISSN： 2434-1177  Document type： Proceedings
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)
Abstract/Point：
Abstract/Point
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Low Endotoxin Recovery (LER) i...
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distribution

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,...
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Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
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particle distribution

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,...
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Author keywords (5)：
Low Endotoxin Recovery

About Low Endotoxin Recovery

, 
リムルス試薬

About リムルス試薬

, 
エンドトキシン

About エンドトキシン

, 
キレート剤

About キレート剤

, 
界面活性剤

About 界面活性剤

JST classification (1)：
JST classification
Category name(code) classified by JST.
Microorganism biochemistry 
(EG03020N)

About Microorganism biochemistry

Reference (7)：
  • 1) Eaton J : LER : The Challenge of Meeting Regulatory Expectations. PDA Lett 51 (10) : 22, 2015
  • 2) Chen D, Wintzingerode F, Eaton J, et al. : PDA LER Task Force Holds its First Workshop. PDA Lett 52 (8) : 16-18, 2016
  • 3) Hughes PF, Thomas C, Suvarna K, et al. : Low Endotoxin Recovery : An FDA Perspective. BioPharma Asia 4 : 14-25, 2015
  • 4) Reich J, Lang P, Grallert H, et al. : Masking of endotoxin in surfactant samples : Effects on Limulus-based detection systems. Biologicals 44 : 417-422, 2016
  • 5) Bolden JS, Warburton RE, Phelan R, et al. : Endotoxin recovery using limulus amebocyte lysate (LAL) assay. Biologicals 44 : 434-440, 2016
ｍore...
Terms in the title (4)：
Terms in the title
Keywords automatically extracted from the title.
キレート剤

About キレート剤

, 
界面活性剤

About 界面活性剤

, 
エンドトキシン

About エンドトキシン

, 
活性

About 活性


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