Art
J-GLOBAL ID：201902280082530853   Reference number：19A0865107

Anti-cancer activity of m-carborane-containing trimethoxyphenyl derivatives through tubulin polymerization inhibition

チューブリン重合阻害によるm-カルボラン含有トリメトキシフェニル誘導体の抗癌活性【JST・京大機械翻訳】
Author (3)：
Kaise Asako

About Kaise Asako

(Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan)

About Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan

, 
Endo Yasuyuki

About Endo Yasuyuki

(Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan)

About Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan

, 
Ohta Kiminori

About Ohta Kiminori

(School of Pharmacy, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan)

About School of Pharmacy, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan


Material：
Bioorganic & Medicinal Chemistry  (Bioorganic and Medicinal Chemistry)

About Bioorganic & Medicinal Chemistry


Volume： 27  Issue： 6  Page： 1139-1144  Publication year： 2019 
JST Material Number： W0556A  ISSN： 0968-0896  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)
Abstract/Point：
Abstract/Point
Japanese summary of the article(about several hundred characters).
All summary is available on JDreamIII(charged).
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m-Carborane-containing compoun...
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Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
screening(inspection)

About screening(inspection)

, 
*polymerization

About polymerization

, 
boron compound

About boron compound

, 
methoxy group

About methoxy group

, 
*tubulin

About tubulin

, 
diastereomer

About diastereomer

, 
structure-activity relationship

About structure-activity relationship

, 
lead compound

About lead compound

, 
*carborane

About carborane

, 
*antitumor action

About antitumor action


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
ヒト乳癌細胞

About ヒト乳癌細胞

, 
ベンゼン環

About ベンゼン環

, 
アキラル

About アキラル

, 
不斉炭素

About 不斉炭素

, 【Automatic Indexing@JST】
Author keywords (4)：
Anti-cancer activity

About Anti-cancer activity

, 
Carborane

About Carborane

, 
Tubulin polymerization inhibition

About Tubulin polymerization inhibition

, 
Trimethoxyphenyl moiety

About Trimethoxyphenyl moiety

JST classification (2)：
JST classification
Category name(code) classified by JST.
Basic research of antitumor(=antineoplastic)drugs 
(GW16010A)

About Basic research of antitumor(=antineoplastic)drugs

,  Synthesis of drugs 
(GV01030F)

About Synthesis of drugs

Terms in the title (5)：
Terms in the title
Keywords automatically extracted from the title.
チューブリン

About チューブリン

, 
重合阻害

About 重合阻害

, 
カルボラン

About カルボラン

, 
誘導体

About 誘導体

, 
抗癌活性

About 抗癌活性


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