Art

J-GLOBAL ID：201902280244446816   Reference number：19A0883073

In Silico Study, Synthesis, and Cytotoxic Activities of Porphyrin Derivatives

ポルフィリン誘導体のin silico研究,合成および細胞毒性活性【JST・京大機械翻訳】

Author (6)： Kurniawan Fransiska (School of Pharmacy, Bandung Institute of Technology, Jalan Ganesha 10, Bandung 40132, Indonesia) ,  Miura Youhei (Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan) ,  Kartasasmita Rahmana Emran (School of Pharmacy, Bandung Institute of Technology, Jalan Ganesha 10, Bandung 40132, Indonesia) ,  Mutalib Abdul (Center for Radioisotope and Radiopharmaceutical Technology, National Nuclear Energy Agency (BATAN), Serpong, Tangerang 15310, Indonesia) ,  Yoshioka Naoki (Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan) ,  Tjahjono Daryono Hadi (School of Pharmacy, Bandung Institute of Technology, Jalan Ganesha 10, Bandung 40132, Indonesia)
Material： Pharmaceuticals (Web)
Volume： 11  Issue： 1  Page： 8  Publication year： 2018 
JST Material Number： U7257A  ISSN： 1424-8247  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Five known porphyrins, 5,10,15...

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Thesaurus term： *cytotoxicity ,  molecular dynamics ,  tumor cell ,  interaction ,  amyloid beta-protein ,  complex (compound) ,  50% inhibitory concentration ,  anti-proliferative activity ,  Carbonic Anhydrase IX ,  Molecular Dynamics Simulation ,  Cell Line, Tumor ,  *in silico ,  *Porphyrins ,  Amyloid ,  glycoprotein ,  animal protein ,  macrocyclic compound ,  nitrogen heterocyclic compound ,  bridged compound
Semi thesaurus term： 分子ドッキング ,  *ポルフィリン誘導体 , 【Automatic Indexing@JST】

Author keywords (5)： porphyrin derivative ,  molecular dynamics ,  synthesis ,  cytotoxicity ,  cancer cell lines

JST classification (3)： Plant biochemistry  (EH01050J) ,  Cell physiology in general  (EF02010S) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Porphyrin

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Terms in the title (3)： ポルフィリン誘導体 ,  研究 ,  細胞毒性活性