Art

J-GLOBAL ID：201902280947690203   Reference number：19A2823225

Metabolic analysis reveals evidence for branched chain amino acid catabolism crosstalk and the potential for improved treatment of organic acidurias

代謝分析は分岐鎖アミノ酸異化クロストークの証拠と有機酸尿症の治療改善の可能性を明らかにする【JST・京大機械翻訳】

Author (6)： McCalley Stephen (University of Pittsburgh School of Medicine, UPMC Children’s Hospital of Pittsburgh, 4401 Penn Ave, Pittsburgh, PA 15224, USA) ,  Pirman David (Agios Pharmaceuticals, 88 Sydney St, Cambridge, MA 02139, USA) ,  Clasquin Michelle (Agios Pharmaceuticals, 88 Sydney St, Cambridge, MA 02139, USA) ,  Johnson Kendall (Agios Pharmaceuticals, 88 Sydney St, Cambridge, MA 02139, USA) ,  Jin Shengfang (Agios Pharmaceuticals, 88 Sydney St, Cambridge, MA 02139, USA) ,  Vockley Jerry (University of Pittsburgh School of Medicine, UPMC Children’s Hospital of Pittsburgh, 4401 Penn Ave, Pittsburgh, PA 15224, USA)
Material： Molecular Genetics and Metabolism  (Mol Genet Metab)
Volume： 128  Issue： 1-2  Page： 57-61  Publication year： 2019 
JST Material Number： E0820A  ISSN： 1096-7192  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Branched chain amino acid (BCA...

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Thesaurus term： dehydrogenase ,  *side chain ,  heredity ,  fibroblast ,  odd number ,  metabolite ,  *dissimilation ,  enzyme ,  *branched-chain amino acid ,  mutation ,  *organic acid ,  characterization ,  *crosstalk(interaction) ,  aliphatic amine ,  aliphatic carboxylic acid ,  primary amine

JST classification (4)： Cheese  (FJ12025C) ,  Metabolism and nutrition  (EG03054K) ,  Gene expression  (EC02040Q) ,  Miscellaneous analytical methods of organic compounds  (CC08034J)

Substance index (2)： Isoleucine ,  Leucine

Terms in the title (10)： 代謝 ,  分析 ,  分岐鎖アミノ酸 ,  異化 ,  クロストーク ,  証拠 ,  有機酸 ,  尿 ,  治療 ,  可能性