Art

J-GLOBAL ID：201902281698756186   Reference number：19A2733733

Long-term administration of excess zinc impairs learning and memory in aged mice

過剰亜鉛の長期投与は老齢マウスの学習と記憶を損なう

Author (6)： Yoshida Kaoru (Department of Food Science and Nutrition, Doshisha Women’s College of Liberal Arts) ,  Gi Min (Department of Molecular Pathology, Osaka City University Graduate School of Medicine) ,  Gi Min (Current address: Department of Environmental Risk Assessment, Osaka City University Graduate School of Medicine) ,  Fujioka Masaki (Department of Molecular Pathology, Osaka City University Graduate School of Medicine) ,  Teramoto Isao (Department of Parasitology, Osaka City University Graduate School of Medicine) ,  Wanibuchi Hideki (Department of Molecular Pathology, Osaka City University Graduate School of Medicine)
Material： Journal of Toxicological Sciences  (J Toxicol Sci)
Volume： 44  Issue： 10  Page： 681-691(J-STAGE)  Publication year： 2019 
JST Material Number： Z0265B  ISSN： 0388-1350  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *zinc ,...
Semi thesaurus term： Y迷路 ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=19A2733733&from=J-GLOBAL&jstjournalNo=Z0265B") }}

Author keywords (6)： Zinc ,  Mice ,  Learning and memory ,  Excess intake ,  Behavioral test ,  Neurodegenerative disorder

JST classification (2)： Toxicity of metals and metal compounds  (GZ02022V) ,  Basic neurology  (GN01020W)

Reference (40)：

• Akiyama, H., Hosokawa, M., Kametani, F., Kondo, H., Chiba, M., Fukushima, M. and Tabira, T. (2012): Long-term oral intake of aluminium or zinc does not accelerate Alzheimer pathology in AβPP and AβPP/tau transgenic mice. Neuropathology, 32, 390-397.
• Antunes, M. and Biala, G. (2012): The novel object recognition memory: neurobiology, test procedure, and its modifications. Cogn. Process., 13, 93-110.
• Barnham, K.J. and Bush, A.I. (2008): Metals in Alzheimer’s and parkinson’s diseases. Curr. Opin. Chem. Biol., 12, 222-228.
• Boruchowska, M., Lankosz, M., Adamek, D. and Korman, A. (2001): PIXE analysis of human brain tissue. XRay Spectrom., 30, 174-179.
• Boyd-Kimball, D., Sultana, R., Mohmmad-Abdul, H. and Butterfield, D.A. (2004): Rodent Aβ(1-42) exhibits oxidative stress properties similar to those of human Aβ(1-42): implications for proposed mechanisms of toxicity. J. Alzheimers Dis., 6, 515-525.

Terms in the title (5)： 亜鉛 ,  長期投与 ,  老齢 ,  マウス ,  学習