Art

J-GLOBAL ID：201902282680123552   Reference number：19A1281192

Imaging of Metastatic Cancer Cells in Sentinel Lymph Nodes using Affibody Probes and Possibility of a Theranostic Approach

アフィボディプローブを用いたセンチネルリンパ節における転移性癌細胞のイメージングとセラノスティック法の可能性【JST・京大機械翻訳】

Author (14)： Tsuchimochi Makoto (Emeritus Professor, The Nippon Dental University, Tokyo, Japan, formerly of the Department of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata, 1-8 Hamaura-cho, Chuo-ku, Niigata 951-8580, Japan) ,  Yamaguchi Haruka (Department of Life Science Dentistry, The Nippon Dental University, 1-9-20 Fujimi, Chiyoda-ku, Tokyo 102-8159, Japan) ,  Yamaguchi Haruka (Department of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata 951-8580, Japan) ,  Yamaguchi Haruka (Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, 28 Woodville Road Woodville South, SA 5011, Australia) ,  Hayama Kazuhide (Department of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata 951-8580, Japan) ,  Okada Yasuo (Department of Pathology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata 951-8580, Japan) ,  Kawase Tomoyuki (Division of Oral Bioengineering, Institute of Medicine and Dentistry, Niigata University, Division of Oral Bioengineering, Department of Tissue Regeneration and Reconstitution, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8541, Japan) ,  Suzuki Takamasa (Department of Electrical and Electronic Engineering, Faculty of Engineering, Niigata University, Niigata 950-2181, Japan) ,  Tsubokawa Norio (Faculty of Engineering, Niigata University, Niigata 950-2181, Japan) ,  Wada Noriaki (Department of General Surgery, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Chiba 272-8513, Japan) ,  Ochiai Atsushi (Division of Biomarker Discovery, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba 277-8577, Japan) ,  Ochiai Atsushi (Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba 277-8561, Japan) ,  Fujii Satoshi (Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba 277-8577, Japan) ,  Fujii Hirofumi (Division of Functional Imaging, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba 277-8577, Japan)
Material： International Journal of Molecular Sciences (Web)  (Int J Mol Sci (Web))
Volume： 20  Issue： 2  Page： 427  Publication year： 2019 
JST Material Number： U7038A  ISSN： 1422-0067  CODEN： IJMCFK  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The accurate detection of lymp...

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Thesaurus term： *probe ,  visualization ,  lymph node metastasis ,  tumor ,  scintigraphy ,  *Lymph ,  Fluorescence ,  human ,  heterotrans plantation ,  Biopsy ,  *lymph node ,  immunohistochemistry ,  near infrared radiation ,  *image processing ,  fluorescence imaging ,  *Sentinel Lymph Node ,  Technology ,  image technology ,  *body fluid ,  clinical laboratory test

Author keywords (10)： sentinel lymph node ,  molecular imaging ,  affibody ,  EGFR ,  HER2 ,  near-infrared fluorescence ,  scintigraphy ,  image-guided surgery ,  photoimmunotherapy ,  theranostics

JST classification (2)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Diagnosis of tumors(=neoplasms)  (GE03020J)

Reference (45)：

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• Thompson, C.F.; St John, M.A.; Lawson, G.; Grogan, T.; Elashoff, D.; Mendelsohn, A.H. Diagnostic value of sentinel lymph node biopsy in head and neck cancer: A meta-analysis. Eur. Arch. Oto-Rhino-Laryngol. 2013, 270, 2115-2122.
• Tsuchimochi, M.; Hayama, K.; Oda, T.; Togashi, M.; Sakahara, H. Evaluation of the efficacy of a small CdTe gamma-camera for sentinel lymph node biopsy. J. Nucl. Med. Off. Publ. Soc. Nucl. Med. 2008, 49, 956-962.

Terms in the title (6)： センチネルリンパ節 ,  転移性 ,  癌細胞 ,  イメージング ,  スティック ,  可能性