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J-GLOBAL ID：201902283069110196   Reference number：19A1298856

FK506 (tacrolimus) causes pain sensation through the activation of transient receptor potential ankyrin 1 (TRPA1) channels

FK506(タクロリムス)はtransient receptor potential ankyrin1(TRPA1)チャンネルの活性化を介して痛覚を惹起する

Author (7)： Kita Tomo (Department of Physiological Science and Molecular Biology, Fukuoka Dental College, Fukuoka, Japan) ,  Uchida Kunitoshi (Department of Physiological Science and Molecular Biology, Fukuoka Dental College, Fukuoka, Japan) ,  Kato Kenichi (Department of Physiological Science and Molecular Biology, Fukuoka Dental College, Fukuoka, Japan) ,  Suzuki Yoshiro (Division of Cell Signaling, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki, Japan) ,  Tominaga Makoto (Division of Cell Signaling, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki, Japan) ,  Tominaga Makoto (Thermal Biology Group, Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, Okazaki, Japan) ,  Yamazaki Jun (Department of Physiological Science and Molecular Biology, Fukuoka Dental College, Fukuoka, Japan)
Material： Journal of Physiological Sciences (Web)
Volume： 69  Issue： 2  Page： 305-316  Publication year： 2019 
JST Material Number： U1505A  ISSN： 1880-6546  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： knockout mouse ,...
Semi thesaurus term： *TRPA1 ,...

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Author keywords (5)： FK506 ,  Pain ,  TRPA1 ,  Sensory neuron ,  Adverse effect

JST classification (3)： Basic research of drugs acting on integumentum commune  (GW12010Y) ,  Poisoning in general  (GD06010Q) ,  Other senses  (EJ13040X)

Substance index (1)： Tacrolimus

Terms in the title (6)： FK506 ,  タクロリムス ,  TRPA1 ,  チャンネル ,  活性化 ,  痛覚