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J-GLOBAL ID：201902283690468894   Reference number：19A0860712

DNA demethylation with 5-aza-2′-deoxycytidine induces the senescence-associated secretory phenotype in the immortal fish cell line, EPC

5-アザ-2′-デオキシシチジンによるDNA脱メチル化は不死魚細胞系,EPCにおける老化関連分泌表現型を誘導する【JST・京大機械翻訳】

Author (3)： Futami Kunihiko (Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan) ,  Maita Masashi (Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan) ,  Katagiri Takayuki (Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan)
Material： Gene  (International Journal Focusting on Gene Cloning and Gene Structure and Function)
Volume： 697  Page： 194-200  Publication year： 2019 
JST Material Number： E0701B  ISSN： 0378-1119  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Fish cell lines are known to b...

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Thesaurus term： Danio rerio ,  p53 protein ,  *secretion (physiology) ,  *Phenotype ,  cell aging ,  Up-Regulation ,  quantitative polymerase chain reaction ,  beta-Galactosidase ,  Cell Proliferation ,  *senile change ,  Telomerase ,  p21 ,  DNA Methylation ,  *Cell Line

Author keywords (7)： Telomerase ,  5-Aza-2′-deoxycytidine ,  EPC ,  Mitotic catastrophe ,  SA-β-gal ,  SASP ,  Teleost

JST classification (2)： Gene expression  (EC02040Q) ,  Structure and chemistry of genes  (EC02020U)

Substance index (1)： 5-Aza-2'-deoxycytidine

Terms in the title (6)： デオキシシチジン ,  DNA脱メチル化 ,  細胞系 ,  EPC ,  老化関連分泌表現型 ,  誘導