Art

J-GLOBAL ID：201902284249518575   Reference number：19A2230137

Lens-specific deletion of the Msx2 gene increased apoptosis by enhancing the caspase-3/caspase-8 signaling pathway

カスパーゼ-3/カスパーゼ-8シグナル伝達経路の増強によりアポトーシスを増加させたMSX2遺伝子の水晶体特異的欠失【JST・京大機械翻訳】

Author (8)： Yu Ziyan (Department of Ophthalmology, Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Provincial Key Laboratory of Lens Research, Shenyang, China) ,  Yu Ziyan (Keck School of Medicine, University of Southern California, Los Angeles, CA, USA) ,  Yu Wenting (Department of Ophthalmology, Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Provincial Key Laboratory of Lens Research, Shenyang, China) ,  Liu Jia (Department of Ophthalmology, Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Provincial Key Laboratory of Lens Research, Shenyang, China) ,  Wu Danhong (Department of Neurology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China) ,  Wang Chunxia (Department of Ophthalmology, Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Provincial Key Laboratory of Lens Research, Shenyang, China) ,  Zhang Jinsong (Department of Ophthalmology, Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Provincial Key Laboratory of Lens Research, Shenyang, China) ,  Zhao Jiangyue (Department of Ophthalmology, Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Provincial Key Laboratory of Lens Research, Shenyang, China)
Material： Journal of International Medical Research  (J Int Med Res)
Volume： 46  Issue： 7  Page： 2843-2855  Publication year： 2018 
JST Material Number： T0238A  ISSN： 1473-2300  CODEN： JIMRBV  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Objective: To investigate the ...

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Thesaurus term： down-regulation ,  *gene ,  up-regulation ,  mouse(animal) ,  knockout mouse ,  *apoptosis ,  wild type ,  mRNA ,  shake out ,  *lens(eye) ,  *caspase
Semi thesaurus term： カスパーゼ3 ,  小眼球症 ,  出生 ,  *伝達経路 , 【Automatic Indexing@JST】

Author keywords (6)： Msx2 ,  apoptosis ,  FoxE3 ,  lens development ,  Casp3 ,  Casp8

JST classification (3)： Development(=generation)and differentiation  (EJ16020W) ,  Structure and chemistry of genes  (EC02020U) ,  Basic dentistry(= odontology)  (GT01020O)

Terms in the title (8)： カスパーゼ ,  カスパーゼ-8 ,  シグナル伝達経路 ,  増強 ,  アポトーシス ,  Msx2遺伝子 ,  水晶体 ,  欠失