Art

J-GLOBAL ID：201902285350549634   Reference number：19A1814794

Efficient Synthesis of 1,9-Substituted Benzo[h][1,6]naphthyridin-2(1H)-ones and Evaluation of their Plasmodium falciparum Gametocytocidal Activities

1,9-置換ベンゾ[h][1,6]ナフチリジン-2(1H)-オン類の効率的合成とそれらのPlasmodium falciparum配偶子細胞活性の評価【JST・京大機械翻訳】

Author (16)： Li Hao (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States) ,  Sun Wei (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States) ,  Huang Xiuli (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States) ,  Lu Xiao (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States) ,  Patel Paresma R. (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States) ,  Kim Myunghoon (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States) ,  Orr Meghan J. (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States) ,  Fisher Richard M. (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States) ,  Tanaka Takeshi Q (Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Maryland, United States) ,  McKew John C. (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States) ,  Simeonov Anton (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States) ,  Sanderson Philip E. (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States) ,  Zheng Wei (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States) ,  Williamson Kim C. (Department of Biology, Loyola University Chicago, Illinois, United States) ,  Williamson Kim C. (Microbiology and Immunology Department, Uniformed Services University of the Health Sciences, Maryland, United States) ,  Huang Wenwei (National Center for Advancing Translational Sciences, National Institutes of Health, Maryland, United States)
Material： ACS Combinatorial Science  (ACS Comb Sci)
Volume： 19  Issue： 12  Page： 748-754  Publication year： 2017 
JST Material Number： W1756A  ISSN： 2156-8952  CODEN： ACSCCC  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： A novel three-component, two-s...

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Thesaurus term： Parasites ,  *gamete ,  growth inhibition ,  coupling reaction ,  survival ratio ,  *Plasmodium falciparum ,  Malaria ,  analogical material ,  one-pot synthesis ,  synthetic pathways ,  intramolecular cyclization ,  aromatic substitution ,  *cell activity ,  anti-malarial activity ,  *microorganism ,  *protozoa ,  *Sporozoa
Semi thesaurus term： 抗マラリア活性 , 【Automatic Indexing@JST】

Author keywords (6)： quinoline ,  benzo[h][1 6]naphthyridin-2(1H)-ones ,  Torin ,  one-pot reaction ,  malaria ,  gametocytocidal activity

JST classification (1)： Peptides  (CF10080G)

Terms in the title (5)： 置換 ,  Plasmodium ,  配偶子 ,  細胞活性 ,  評価