Art

J-GLOBAL ID：201902287241801350   Reference number：19A2459269

Susceptibility, Safety and Clinical Outcome of a Fixed-dose (24g/day) of a Combination of Ampicillin and Cloxacillin for Infective Endocarditis as Empiric Therapy: Retrospective Study

感染性心内膜炎における初期治療薬としてのAmpicillin/Cloxacillin(1:1)配合剤(24g/日)の感受性・安全性・アウトカム検討

Author (8)： AZECHI TAKUYA (順天堂大 医 順天堂医院 薬剤部) ,  HIRAI YUJI (順天堂大 医 総合診療科) ,  UEHARA YUKI (順天堂大 医 総合診療科) ,  SASANO HIROSHI (順天堂大 医 順天堂医院 薬剤部) ,  YOSHIZAWA TOSHIHIRO (順天堂大 医 順天堂医院 薬剤部) ,  MATSUMOTO HIROSHI (順天堂大 医 順天堂医院 薬剤部) ,  AOSHIMA MIZUKI (順天堂大 医 順天堂医院 薬剤部) ,  NAITO TOSHIO (順天堂大 医 総合診療科)
Material： 感染症学雑誌  (Journal of the Japanese Association for Infectious Diseases)
Volume： 93  Issue： 5  Page： 649-654  Publication year： Sep. 20, 2019 
JST Material Number： Z0760A  ISSN： 0387-5911  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *bacterial endocarditis ,...
Semi thesaurus term： *Ampicillin/Cloxacillin ,...

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JST classification (3)： Treatment for infectious diseases,parasitic diseases.  (GD01030D) ,  Clinical application of antibiotics acting on pathogenic organisms  (GX05030N) ,  Drug therapy(=pharmacotherapy)for cardiovascular system diseases  (GJ05020M)

Reference (19)：

• 1) Habit G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F, et al.:2015 ESC Guidelines for the management of infective endocarditis : The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by : European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). Eur Heart J 2015;36(44):3075-128.
• 2) Fong IW:Staphylococcal central nervous system infections treated with cloxacillin. J Antimicrob Chemother 1983;12(6):607-12.
• 3) Pierce D, Calkins BC, Thornton K:Infectious endocarditis : diagnosis and treatment. Am Fam Physician 2012;85(10):981-6.
• 4) Nagai T, Takase Y, Hamabe A, Tabata H:Observational study of infective endocarditis at a community-based hospital : dominance of elderly patients with comorbidity. Intern Med 2018;57 (3):301-10.
• 5) Selton-Suty C, Celard M, Le Moing V, Doco-Lecompte T, Chirouze C, Lung B, et al.:Preeminence of staphylococcus aureus in infective endocarditis : a 1-year population-based survey. Clin Infect Dis 2012;54(9):1230-9.

Terms in the title (6)： 感染性心内膜炎 ,  初期治療 ,  配合剤 ,  感受性 ,  安全性 ,  アウトカム