Art

J-GLOBAL ID：201902287641653772   Reference number：19A2444738

Methods for the expression, purification, and crystallization of histone deacetylase 6-inhibitor complexes

ヒストンデアセチラーゼ6阻害剤複合体の発現,精製および結晶化のための方法【JST・京大機械翻訳】

Author (2)： Osko Jeremy D. (Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA, United States) ,  Christianson David W. (Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA, United States)
Material： Methods in Enzymology  (Methods Enzymol)
Volume： 626  Page： 447-474  Publication year： 2019 
JST Material Number： T0576A  ISSN： 0076-6879  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Histone deacetylase (HDAC) iso...

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Thesaurus term： side effect ,  tubulin ,  isozyme ,  gene ,  zinc ,  *complex(substance) ,  *histone deacetylase ,  plasmid ,  apoptosis ,  crystal structure ,  human(primates) ,  *crystallization ,  CD2 antigen
Semi thesaurus term： ドメイン構造 ,  *阻害剤 , 【Automatic Indexing@JST】

Author keywords (5)： Zinc enzyme ,  Epigenetics ,  Tubulin ,  Protein crystallography ,  Drug design

JST classification (4)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Cell physiology in general  (EF02010S) ,  Enzyme in general  (EB09010D)

Terms in the title (6)： ヒストンデアセチラーゼ6 ,  阻害剤 ,  複合体 ,  発現 ,  精製 ,  結晶化