Art

J-GLOBAL ID：201902289453518933   Reference number：19A2020900

Novel dodecyl-containing azido and glucuronamide-based nucleosides exhibiting anticancer potential

抗癌剤の可能性を示す新規なドデシル含有アジドおよびglucuronアミドに基づくヌクレオシド【JST・京大機械翻訳】

Author (7)： Xavier Nuno M. (Centro de Quimica e Bioquimica, Faculdade de Ciencias, Universidade de Lisboa, Ed. C8, 2°/5° Piso, Campo Grande, 1749-016 Lisboa, Portugal) ,  Xavier Nuno M. (Centro de Quimica Estrutural, Faculdade de Ciencias, Universidade de Lisboa, Lisboa, Portugal) ,  Goncalves-Pereira Rita (Centro de Quimica e Bioquimica, Faculdade de Ciencias, Universidade de Lisboa, Ed. C8, 2°/5° Piso, Campo Grande, 1749-016 Lisboa, Portugal) ,  Goncalves-Pereira Rita (Centro de Quimica Estrutural, Faculdade de Ciencias, Universidade de Lisboa, Lisboa, Portugal) ,  Jorda Radek (Laboratory of Growth Regulators, Centre of the Region Hana for Biotechnological and Agricultural Research, Palacky University and Institute of Experimental Botany, the Czech Academy of Sciences, Slechtitelu 27, 78371 Olomouc, Czech Republic) ,  Hendrychova Denisa (Laboratory of Growth Regulators, Centre of the Region Hana for Biotechnological and Agricultural Research, Palacky University and Institute of Experimental Botany, the Czech Academy of Sciences, Slechtitelu 27, 78371 Olomouc, Czech Republic) ,  Oliveira M. Conceicao (Centro de Quimica Estrutural, Instituto Superior Tecnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal)
Material： Pure and Applied Chemistry  (Chimie Pure et Appliquee)
Volume： 91  Issue： 7  Page： 1085-1105  Publication year： 2019 
JST Material Number： H0385A  ISSN： 0033-4545  CODEN： PACHAS  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: The synthesis and an...

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Thesaurus term： apoptosis ,  *azide(organic) ,  silylation ,  antitumor action ,  benzylation ,  *nucleoside ,  breast tumor ,  metabolite ,  metabolic pathway ,  purine nucleoside ,  *antitumor drug ,  cell cycle ,  protein ,  nitrogen heterocyclic compound ,  urea compound ,  hydroxy compound

Author keywords (6)： anticancer activity ,  apoptosis ,  azido nucleosides ,  glucuronamide-based nucleosides ,  ICS-29 ,  nucleoside analogs

JST classification (3)： Nucleic acids in general  (EB04010U) ,  Stereochemistry of organic reaction  (CF02130V) ,  Platinum family element complexes  (CE01100E)

Substance index (2)： Purine ,  Uracil

Terms in the title (5)： 抗癌剤 ,  可能性 ,  アジド ,  アミド ,  ヌクレオシド