Art

J-GLOBAL ID：201902290647624985   Reference number：19A1491359

Specific binding of PCBP1 to heavily oxidized RNA to induce cell death

細胞死を誘導する高酸化RNAへのPCBP1の特異的結合【JST・京大機械翻訳】

Author (5)： Ishii Takashi (Department of Biochemistry, Fukuoka Dental College, 814-0193 Fukuoka, Japan) ,  Hayakawa Hiroshi (Department of Biochemistry, Fukuoka Dental College, 814-0193 Fukuoka, Japan) ,  Igawa Tatsuhiro (Frontier Research Center, Fukuoka Dental College, 814-0193 Fukuoka, Japan) ,  Sekiguchi Takeshi (Department of Molecular Biology, Graduate School of Medical Sciences, Kyushu University, 812-8582 Fukuoka, Japan) ,  Sekiguchi Mutsuo (Frontier Research Center, Fukuoka Dental College, 814-0193 Fukuoka, Japan)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 115  Issue： 26  Page： 6715-6720  Publication year： 2018 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： In aerobically growing cells, ...

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Thesaurus term： *RNA ,  hydrogen peroxide ,  human(primates) ,  gene expression ,  robustness ,  survival ratio ,  wild type ,  apoptosis ,  mRNA ,  *oxidation ,  nitrogen heterocyclic compound ,  hydroxy compound
Semi thesaurus term： ドメイン構造 ,  Cas9 ,  オリゴリボヌクレオチド ,  AUF1 , 【Automatic Indexing@JST】

Author keywords (3)： oxidative stress ,  RNA-binding protein ,  apoptosis

JST classification (1)： Biological function  (EB03040U)

Substance index (1)： Guanine

Terms in the title (4)： 細胞死 ,  誘導 ,  酸化 ,  RNA