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J-GLOBAL ID：201902291065125384   Reference number：19A1492381

Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex

Atg2a-Wipi4複合体の構造的および生化学的分析からのオートファゴソーム生合成への洞察【JST・京大機械翻訳】

Author (8)： Chowdhury Saikat (Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037) ,  Otomo Chinatsu (Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037) ,  Leitner Alexander (Department of Biology, Institute of Molecular Systems Biology, Eidgenossische Technische Hochschule Zuerich, 8093 Zurich, Switzerland) ,  Ohashi Kazuto (Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037) ,  Aebersold Ruedi (Department of Biology, Institute of Molecular Systems Biology, Eidgenossische Technische Hochschule Zuerich, 8093 Zurich, Switzerland) ,  Aebersold Ruedi (Faculty of Science, University of Zurich, 8093 Zurich, Switzerland) ,  Lander Gabriel C. (Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037) ,  Otomo Takanori (Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 115  Issue： 42  Page： E9792-E9801  Publication year： 2018 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Autophagy is an enigmatic cell...

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Thesaurus term： cell junction ,  lysosome ,  *biosynthesis ,  mass spectrometry ,  phagocyte ,  Autophagy ,  effector ,  *complex (substance) ,  Phagocytosis ,  lipid membrane ,  electron microscopy ,  human ,  characterization ,  single particle ,  *Autophagosomes ,  Cell Physiological Phenomena

Author keywords (5)： autophagy ,  ATG2 ,  membrane tethering ,  single-particle analysis ,  chemical cross-linking coupled with mass spectrometry

JST classification (2)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Terms in the title (5)： 複合体 ,  生化学的分析 ,  オートファゴソーム ,  生合成 ,  洞察