Art

J-GLOBAL ID：201902291174456678   Reference number：19A1491796

p53-inducible DPYSL4 associates with mitochondrial supercomplexes and regulates energy metabolism in adipocytes and cancer cells

p53誘導性DPYSL4はミトコンドリア超複合体と会合し,脂肪細胞と癌細胞におけるエネルギー代謝を調節する【JST・京大機械翻訳】

Author (31)： Nagano Hidekazu (Department of Clinical Cell Biology and Medicine, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Nagano Hidekazu (Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology, 100-8055 Tokyo, Japan) ,  Hashimoto Naoko (Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology, 100-8055 Tokyo, Japan) ,  Hashimoto Naoko (Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Nakayama Akitoshi (Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology, 100-8055 Tokyo, Japan) ,  Nakayama Akitoshi (Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Suzuki Sawako (Department of Clinical Cell Biology and Medicine, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Suzuki Sawako (Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology, 100-8055 Tokyo, Japan) ,  Miyabayashi Yui (Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Yamato Azusa (Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology, 100-8055 Tokyo, Japan) ,  Yamato Azusa (Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Higuchi Seiichiro (Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology, 100-8055 Tokyo, Japan) ,  Higuchi Seiichiro (Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Fujimoto Masanori (Department of Clinical Cell Biology and Medicine, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Fujimoto Masanori (Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology, 100-8055 Tokyo, Japan) ,  Sakuma Ikki (Department of Clinical Cell Biology and Medicine, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Sakuma Ikki (Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology, 100-8055 Tokyo, Japan) ,  Beppu Minako (Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology, 100-8055 Tokyo, Japan) ,  Beppu Minako (Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Yokoyama Masataka (Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology, 100-8055 Tokyo, Japan) ,  Yokoyama Masataka (Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Suzuki Yutaka (Department of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo, 277-8562 Chiba, Japan) ,  Sugano Sumio (Department of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo, 277-8562 Chiba, Japan) ,  Ikeda Kazuhiro (Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, 350-1241 Saitama, Japan) ,  Tatsuno Ichiro (Center for Diabetes, Metabolism and Endocrinology, Toho University Sakura Medical Center, 285-8741 Chiba, Japan) ,  Manabe Ichiro (Department of Disease Biology and Molecular Medicine, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Yokote Koutaro (Department of Clinical Cell Biology and Medicine, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan) ,  Inoue Satoshi (Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, 350-1241 Saitama, Japan) ,  Inoue Satoshi (Department of Functional Biogerontology, Tokyo Metropolitan Institute of Gerontology, 173-0015 Tokyo, Japan) ,  Tanaka Tomoaki (Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology, 100-8055 Tokyo, Japan) ,  Tanaka Tomoaki (Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, 260-8670 Chiba, Japan)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 115  Issue： 33  Page： 8370-8375  Publication year： 2018 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： The tumor suppressor p53 regul...

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Thesaurus term： *p53 protein ,  *complex (substance) ,  pathophysiology ,  *tumor cell ,  *fat cell ,  *Energy Metabolism ,  gene ,  *Metabolism ,  siRNA ,  Down-Regulation ,  human ,  Obesity ,  pathogenesis ,  *Mitochondria ,  Gene Knockdown Technique ,  overexpression

Author keywords (5)： tumor suppressor p53 ,  mitochondria ,  metabolism ,  cancer ,  obesity

JST classification (3)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Terms in the title (8)： p53 ,  ミトコンドリア ,  複合体 ,  会合 ,  脂肪細胞 ,  癌細胞 ,  エネルギー代謝 ,  調節