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J-GLOBAL ID：201902291982625036   Reference number：19A1928419

Recurrent short-term hypoglycemia and hyperglycemia induce apoptosis and oxidative stress via the ER stress response in immortalized adult mouse Schwann (IMS32) cells

再発性の短期低血糖と高血糖は不死化成体マウスSchwann(IMS32)細胞におけるERストレス応答を介してアポトーシスと酸化ストレスを誘導する

Author (10)： Kato Ayako (Laboratory of Medicine, Aichi Gakuin University School of Pharmacy, Chikusa-ku, Nagoya, Aichi, 464-8650, Japan) ,  Tatsumi Yasuaki (Laboratory of Medicine, Aichi Gakuin University School of Pharmacy, Chikusa-ku, Nagoya, Aichi, 464-8650, Japan) ,  Yako Hideji (Diabetic Neuropathy Project, Department of Sensory and Motor Systems, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, 156-8506 Japan) ,  Sango Kazunori (Diabetic Neuropathy Project, Department of Sensory and Motor Systems, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, 156-8506 Japan) ,  Himeno Tatsuhito (Division of Diabetes, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Aichi, 480-1195, Japan) ,  Kondo Masaki (Division of Diabetes, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Aichi, 480-1195, Japan) ,  Kato Yoshiro (Division of Diabetes, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Aichi, 480-1195, Japan) ,  Kamiya Hideki (Division of Diabetes, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Aichi, 480-1195, Japan) ,  Nakamura Jiro (Division of Diabetes, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Aichi, 480-1195, Japan) ,  Kato Koichi (Laboratory of Medicine, Aichi Gakuin University School of Pharmacy, Chikusa-ku, Nagoya, Aichi, 464-8650, Japan)
Material： Neuroscience Research  (神経科学)
Volume： 147  Page： 26-32  Publication year： Oct. 2019 
JST Material Number： D0210C  ISSN： 0168-0102  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： Mus musculus ,...
Semi thesaurus term： blood physiology ,...

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Author keywords (7)： Diabetic neuropathy ,  Hypoglycemia ,  Hyperglycemia ,  Glucose fluctuation ,  Schwann cells ,  Oxidative stress ,  Endoplasmic reticulum (ER) stress

JST classification (4)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Cell physiology in general  (EF02010S) ,  Nervous system in general  (EJ12010J) ,  Basic neurology  (GN01020W)

Substance index (1)： 4-Phenylbutyric acid

Terms in the title (13)： 再発 ,  短期 ,  低血糖 ,  高血糖 ,  不死化 ,  成体 ,  マウス ,  細胞 ,  ERストレス ,  応答 ,  アポトーシス ,  酸化ストレス ,  誘導