Art

J-GLOBAL ID：201902292175050040   Reference number：19A1280388

Heterogeneity in Colorectal Cancer: A Challenge for Personalized Medicine?

結腸直腸癌における不均一性:個別化医療への挑戦?【JST・京大機械翻訳】

Author (6)： Molinari Chiara (Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy) ,  Marisi Giorgia (Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy) ,  Passardi Alessandro (Department of Medical Oncology, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy) ,  Matteucci Laura (Department of Medical Oncology, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy) ,  Maio Giulia De (Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy) ,  Ulivi Paola (Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy)
Material： International Journal of Molecular Sciences (Web)  (Int J Mol Sci (Web))
Volume： 19  Issue： 12  Page： 3733  Publication year： 2018 
JST Material Number： U7038A  ISSN： 1422-0067  CODEN： IJMCFK  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： High inter-patient variability...

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Thesaurus term： EGF receptor ,  prognosis ,  tumor ,  therapy ,  literature review ,  human(primates) ,  *Individualized Medicine ,  *heterogeneity ,  characterization
Semi thesaurus term： 個性化 ,  非侵襲 ,  転移性 ,  偽陰性 ,  腫瘍組織 ,  *結腸直腸癌 , 【Automatic Indexing@JST】

Author keywords (7)： heterogeneity ,  colorectal cancer ,  tumor tissue ,  metastasis ,  cfDNA ,  liquid biopsy ,  response to therapy

JST classification (1)： Tumors(=neoplasms)of digestive system  (GH04000D)

Reference (113)：

• Moraga-Serrano, P.E. Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived with Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016: A Systematic Analysis for the Global Burden of Disease Study. JAMA Oncol. 2018, 2018, 126049.
• Siegel, R.; Naishadham, D.; Jemal, A. Cancer Statistics, 2013. CA Cancer J. Clin. 2013, 63, 11-30.
• Van Cutsem, E.; Cervantes, A.; Adam, R.; Sobrero, A.; Van Krieken, J.H.; Aderka, D.; Aranda Aguilar, E.; Bardelli, A.; Benson, A.; Bodoky, G.; et al. ESMO Consensus Guidelines for the Management of Patients with Metastatic Colorectal Cancer. Ann. Oncol. 2016, 27, 1386-1422.
• Malvezzi, M.; Carioli, G.; Bertuccio, P.; Boffetta, P.; Levi, F.; La Vecchia, C.; Negri, E. European Cancer Mortality Predictions for the Year 2018 with Focus on Colorectal Cancer. Ann. Oncol. 2018, 29, 1016-1022.
• Adam, R.; Pascal, G.; Castaing, D.; Azoulay, D.; Delvart, V.; Paule, B.; Levi, F.; Bismuth, H. Tumor Progression while on Chemotherapy: A Contraindication to Liver Resection for Multiple Colorectal Metastases? Ann. Surg. 2004, 240, 1052-1061.

Terms in the title (3)： 結腸直腸癌 ,  不均一性 ,  個別化医療