Murakami Shohei

ムラカミショウヘイ | Murakami Shohei

Affiliation and department：
Job title： Lecturer

Research field (1)： Medical biochemistry

Research theme for competitive and other funds (7)：

2024 - 2027 呼気凝縮液を用いた呼気オミックス解析による慢性移植肺機能不全の病態解明
2024 - 2027 巨核球・赤血球前駆細胞におけるミトコンドリア依存的な分化制御機構の解明
2021 - 2023 Analysis of polysulfide-dependent mitochondrial function in hematopoietic stem cells
2019 - 2020 Study on behavior of myeloproliferative neoplasms originated from one initial site
2015 - 2017 Analysis of hematopoietic stem cell activation induced by Nrf2 inducers

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Papers (21)：

Keito Okazaki, Madoka Kawaguchi, Shohei Murakami, Haruna Takeda, Hiroki Sekine, Osamu Takeuchi, Hozumi Motohashi. Regnase-1 Promotes Tumour-Initiating Activity in Non-Small Cell Lung Cancer. Journal of biochemistry. 2026. 179. 1. 61-74
Shohei Murakami, Yusuke Kusano, Keito Okazaki, Takaaki Akaike, Hozumi Motohashi. NRF2 signalling in cytoprotection and metabolism. British journal of pharmacology. 2026. 183. 1. 101-114
Eunkyu Sung, Shohei Murakami, Masanobu Morita, Tomoaki Ida, Takaaki Akaike, Hozumi Motohashi. Mitochondria regulate the cell fate decisions of megakaryocyte-erythroid progenitors. Stem cell reports. 2025. 20. 12. 102720-102720
Carsten Berndt, Hamed Alborzinia, Vera Skafar Amen, Scott Ayton, Uladzimir Barayeu, Alexander Bartelt, Hülya Bayir, Christina M Bebber, Kivanc Birsoy, Jan P Böttcher, et al. Ferroptosis in health and disease. Redox biology. 2024. 75. 103211-103211
Hiroki Sekine, Haruna Takeda, Norihiko Takeda, Akihiro Kishino, Hayato Anzawa, Takayuki Isagawa, Nao Ohta, Shohei Murakami, Hideya Iwaki, Nobufumi Kato, et al. PNPO-PLP axis senses prolonged hypoxia in macrophages by regulating lysosomal activity. Nature Metabolism. 2024

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MISC (23)：

古森龍太郎, 村上昌平, 守田匡伸, 高田剛, 赤池孝章, 本橋ほづみ, 本橋ほづみ. ミトコンドリア呼吸鎖複合体の超硫黄化修飾の探索および生理学的意義の検討. 日本生化学会大会(Web). 2024. 97th
飯田謙人, 河口まどか, 岡崎慶斗, 武田遥奈, 七野成之, 早坂一希, 早坂一希, 酒井勁, 酒井勁, 岡田克典, et al. Immunological features in NRF2-activated cancers. 日本癌学会学術総会抄録集(Web). 2023. 82nd
岩城英也, 岩城英也, 関根弘樹, 村上昌平, 加藤伸史, 北村洋, 北村洋, 魏范研, 佐藤英世, 福田真嗣, et al. 炎症性腸疾患モデルでのxCT阻害による抗炎症作用. 日本生化学会大会(Web). 2023. 96th
武田遥奈, 村上昌平, 赤池孝章, 澤智裕, 関根弘樹, 本橋ほづみ. 活性化マクロファージがおりなす起炎症反応:システイン代謝から考える. がんと代謝研究会プログラム&抄録集. 2023. 9th
草野佑典, 村上昌平, 本橋ほづみ. エネルギー代謝におけるKEAP1-NRF2制御系と硫黄代謝の役割. 化学と生物. 2023. 61. 4. 188-195

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Lectures and oral presentations (21)：

細胞増殖・分化制御におけるミトコンドリア硫黄代謝の役割
(第143回日本薬学会 2023)
造血幹細胞におけるミトコンドリア内超硫黄分子の生理学的役割(採択済)
(第95回日本生化学会大会)
Physiological function of mitochondrial sulfer metabolism in hematopoietic stem cells(採択済)
(The 12th international conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide)
ミトコンドリア内超硫黄分子の生理学的役割の解明
(第88回日本生化学会東北支部会例会・シンポジウム 2022)
造血細胞分化・維持制御における超硫黄分子の役割
(第21回分子予防環境医学研究会 2022)

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Education (3)：

2010 - 2014 Tohoku University Graduate School of Medicine Department of Medical Sciences (Doctor)
2008 - 2010 Tohoku University Graduate School of Medicine Department of Medical Sciences (Master)
2004 - 2008 Tohoku University Faculty of Science Department of Chemistry

Professional career (1)：

Work history (7)：

2025/09 - 現在 Tohoku University Graduate School of Medicine Lecturer
2024/01 - 2025/08 Tohoku University Graduate School of Medicine assistant professor
2021/04 - 2023/12 Tohoku University Institute of Development, Aging and Cancer Center for Environmental Response Research assistant professor
2020/04 - 2021/03 Tohoku University, Institute of development, aging and cancer Department of gene expression regulation
2017/07 - 2020/03 CEA/DSV/iRCM Research Laboratory on repair and Transcription in hematopoietic Stem Cells Postdoc

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Awards (1)：

Association Membership(s) (4)：

日本癌学会 , 日本免疫学会 , 日本分子生物学会 , 日本生化学会

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