Rchr
J-GLOBAL ID:202001000167535999
Update date: Jun. 19, 2024
Otsuka Kensuke
オオツカ ケンスケ | Otsuka Kensuke
Affiliation and department:
Research field (7):
Applied biofunctional and bioprocess engineering
, Molecular biology
, Molecular biology
, Applied molecular and cellular biology
, Biomedical engineering
, Developmental biology
, Molecular biology
Research keywords (9):
ラボオートメーション
, ライトシート顕微鏡
, 組織透明化
, 環境因子
, Next-generation sequencing
, ライブセルイメージング
, organoids
, 消化管
, 組織幹細胞
Research theme for competitive and other funds (5):
- 2024 - 2028 環境因子に共通するゲノムストレスと炎症の臓器・オルガノイドイメージング
- 2019 - 2023 mTert幹細胞に特異的な遺伝子の解析による幹細胞休止性と放射線抵抗性の理解
- 2012 - 2017 Role of non-homologous end joining in biological response under low dose-rate irradiation condition
- 2013 - 2016 Quantitative evaluation of radiation-induced response on tissue stem cells
- 2011 - 2012 Establishment of spatio-temporal analysis for low-dose-rateradiation-induced damage accumulation in tissue stem cells
Papers (15):
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Kohei Otomo, Takaki Omura, Yuki Nozawa, Steven J. Edwards, Yukihiko Sato, Yuri Saito, Shigehiro Yagishita, Hitoshi Uchida, Yuki Watakabe, Kiyotada Naitou, et al. descSPIM: an affordable and easy-to-build light-sheet microscope optimized for tissue clearing techniques. Nature Communications. 2024. 15. 4941
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Kensuke Otsuka, Toshiyasu Iwasaki. Insights into radiation carcinogenesis based on dose-rate effects in tissue stem cells. International Journal of Radiation Biology. 2023. 99. 10. 1503-1521
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Yuki Fujimichi, Kensuke Otsuka, Masanori Tomita, Toshiyasu Iwasaki. Ionizing radiation alters organoid forming potential and replenishment rate in a dose/dose-rate dependent manner. Journal of radiation research. 2022. 63. 2. 166-173
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Yuki Fujimichi, Kensuke Otsuka, Masanori Tomita, Toshiyasu Iwasaki. An Efficient Intestinal Organoid System of Direct Sorting to Evaluate Stem Cell Competition in Vitro. Scientific Reports. 2019. 9. 1
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Kensuke Otsuka, Masanori Tomita. Concurrent live imaging of DNA double-strand break repair and cell-cycle progression by CRISPR/Cas9-mediated knock-in of a tricistronic vector. Scientific reports. 2018. 8. 1. 17309-17309
more...
MISC (6):
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大塚健介, 藤通有希. Challenges to radiation biology using organoids and live-cell imaging. 放射線生物研究. 2021. 56. 2. 224-235
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大塚 健介. 消化管発がんの起源としての組織幹細胞. 病理と臨床. 2015. 33. 1. 65-69
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岩崎 利泰, 大塚 健介, 冨田 雅典. 低線量・低線量率での放射線影響に関する研究. 電気評論. 2014. 99. 6. 49-54
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大塚 健介, 冨田 雅典, 山内 基弘, 岩崎 利泰. 【放射線被ばくに対する組織反応】放射線被ばくに対する組織反応 腸管. 放射線生物研究. 2014. 49. 2. 211-226
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大塚 健介, 冨田 雅典. 個体・細胞レベルでの低線量生物影響研究 (低線量放射線研究の現況). Den-chu-ken topics. 2011. 8. 9-13
more...
Education (1):
Work history (5):
- 2021/07 - 現在 Central Research Institute of Electric Power Industry
- 2019/07 - 2021/06 Central Research Institute of Electric Power Industry
- 2007/08 - 2019/06 一般財団法人電力中央研究所 原子力技術研究所 放射線安全研究センター 主任研究員
- 2018/04 - 2019/03 Boston Children's Hospital / Harvard Medical School, Division of Endocrinolgy, Research Fellow
- 2003/04 - 2007/07 財団法人電力中央研究所 低線量放射線研究センター 研究員
Association Membership(s) (3):
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