J-GLOBAL ID:202001000803613717   Update date: Nov. 16, 2021

Isobe Shin-Ya

イソベ シンヤ | Isobe Shin-Ya
Affiliation and department:
Job title: 特任助教
Research keywords  (1): DNA damage repair
Research theme for competitive and other funds  (3):
  • 2016 - 2019 Construction of constitutive heterochromatin and facultative heterochromatin
  • 2013 - 2018 Elucidation of structure and function of heterochromatin
  • 2013 - 2015 ヘテロクロマチンにおけるDNA修復メカニズムの解明
Papers (3):
  • Shin-Ya Isobe, Shin-Ichiro Hiraga, Koji Nagao, Hiroyuki Sasanuma, Anne D Donaldson, Chikashi Obuse. Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action. Cell reports. 2021. 36. 2. 109383-109383
  • Shin-Ya Isobe, Koji Nagao, Naohito Nozaki, Hiroshi Kimura, Chikashi Obuse. Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair. CELL REPORTS. 2017. 20. 2. 297-307
  • Mayu Isono, Atsuko Niimi, Takahiro Oike, Yoshihiko Hagiwara, Hiro Sato, Ryota Sekine, Yukari Yoshida, Shin-Ya Isobe, Chikashi Obuse, Ryotaro Nishi, et al. BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation. CELL REPORTS. 2017. 18. 2. 520-532
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