Saeki Kohei

サエキコウヘイ | Saeki Kohei

Affiliation and department：
Job title： Associate Professor

Research field (2)： Tumor biology , Veterinary medicine

Research keywords (2)： Veterinary Oncology , 乳腺生理学

Research theme for competitive and other funds (5)：

2021 - 2022 ウシの乳汁中上皮細胞解析で明らかにする泌乳量と乳腺分化の関係
2018 - 2019 BRAF gene mutation causes hallmarks of cancer associated with tumor microenvironment
2016 - 2018 Significance of BRAF gene mutation on tumor microenvironment
2016 - 2017 磁気トレーサー粒子を用いたがん転移診断における複数トレーサー併用法の原理実証
2014 - 2016 犬悪性乳腺腫瘍に対するミトコンドリア呼吸鎖複合体阻害の抗腫瘍効果に関する研究

Papers (56)：

Shotaro Eto, Daiki Kato, Kohei Saeki, Takaaki Iguchi, Qin Shiyu, Satoshi Kamoto, Ryohei Yoshitake, Masahiro Shinada, Namiko Ikeda, Masaya Tsuboi, et al. Comprehensive Analysis of the Tumour Immune Microenvironment in Canine Urothelial Carcinoma Reveals Immunosuppressive Mechanisms Induced by the COX-Prostanoid Cascade. Veterinary and comparative oncology. 2024
Kohei Saeki, Desiree Ha, Gregory Chang, Hitomi Mori, Ryohei Yoshitake, Xiwei Wu, Jinhui Wang, Yuan-Zhong Wang, Xiaoqiang Wang, Tony Tzeng, et al. Perimenopausal and Menopausal Mammary Glands In A 4-Vinylcyclohexene Diepoxide Mouse Model. Journal of mammary gland biology and neoplasia. 2024. 29. 1. 15-15
Shotaro Eto, Masahiro Shinada, Kohei Saeki, Masaya Tsuboi, Satoshi Kamoto, Ryohei Yoshitake, James Chambers, Kazuyuki Uchida, Daiki Kato, Ryohei Nishimura, et al. Pan-tumour analysis of COX-2 expression in dogs. Veterinary journal (London, England : 1997). 2024. 106064-106064
Ryohei Yoshitake, Hitomi Mori, Desiree Ha, Xiwei Wu, Jinhui Wang, Xiaoqiang Wang, Kohei Saeki, Gregory Chang, Hyun Jeong Shim, Yin Chan, et al. Molecular features of luminal breast cancer defined through spatial and single-cell transcriptomics. Clinical and translational medicine. 2024. 14. 1. e1548
Kosuke Kobayashi, Reika Deja Takemura, Jiro Miyamae, Ikki Mitsui, Kohei Murakami, Kenji Kutara, Kohei Saeki, Teppei Kanda, Yasuhiko Okamura, Akihiko Sugiyama. Phenotypic and molecular characterization of novel pulmonary adenocarcinoma cell lines established from a dog. Scientific Reports. 2023. 13. 1

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MISC (53)：

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Patents (1)：

犬のがんリスク評価方法及びがんリスク評価システム

Books (17)：

実験デザインからわかるシングルセル研究実践テキスト
羊土社 2024 ISBN:9784758122702
獣医外科学 = Veterinary surgery in small animals
朝倉書店 2024 ISBN:9784254460391
腫瘍外科 = Surgical oncology
ファームプレス 2023 ISBN:9784863821170
リアルタイム・デジタルPCR実験スタンダード : 実験の原理から検出・定量・診断まで、現場で生きる完全マニュアル
羊土社 2022 ISBN:9784758122573
カラーアトラス小動物外科シリーズ頭頸部
ファームプレス 2020 ISBN:9784863821118

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Lectures and oral presentations (3)：

Mammary cell atlas suggests canine mammary tumors as a potential model for human metaplastic breast cancer
(2022)
ウェット研究者のシングルセル解析ことはじめ:0からの乳腺上皮細胞アトラス作り
(シングルセルゲノミクス研究会2022 2022)
シングルセルデータ解析セミナー
(10x Genomics - シングルセルゲノミクス研究会共催ウェビナー 2021)

Education (2)：

2011 - 2015 The University of Tokyo Graduate School of Agricultural and Life Sciences Veterinary Medical Sciences
2005 - 2011 The University of Tokyo Faculty of Agriculture Department of Veterinary Medical Science

Professional career (1)：

博士(獣医学)

Work history (8)：

2023/04 - 現在 Okayama University of Science
2020/08 - 2023/03 Okayama University of Science
2018/09 - 2020/06 Beckman Research Institute, City of Hope Department of Cancer Biology Postdoctoral fellow
2017/04 - 2018/09 The University of Tokyo Graduate School of Agricultural and Life Sciences
2016/04 - 2017/03 The University of Tokyo Graduate School of Agricultural and Life Sciences

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Committee career (2)：

2024/06 - 現在 The Veterinary Journal Associate Editor
2022/01 - 2024/06 The Veterinary Journal Advisory Board

Awards (4)：

2019/11 - Breast Cancer and the Environmental Research Program Travel award (Selection for oral presentation) Combined effects of 17β-estradiol (E2), progesterone (P4), and polybrominated diphenyl ethers (PBDEs) on postmenopausal murine mammary glands at the single cell resolution
2016/02 - 日本獣医内科学アカデミー研究アワード(文永堂出版JVM賞) 犬尿路移行上皮癌と前立腺癌におけるdigital PCRによるBRAF遺伝子変異検出法の確立とLiquid biopsyの有用性評価
2016/01 - The Veterinary Journal The Andrew Higgins Prize Phenotypic screening of a library of compounds against metastatic and non-metastatic clones of a canine mammary gland tumour cell line
2014/04 - 第14回東京大学生命科学シンポジウムポスター賞

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