HIRAKI TOMOKA

Research theme for competitive and other funds (3)：

2024 - 2026 由来の異なる間葉系幹細胞培養上清の特性解明と液性因子を応用した骨再生治療法の展開
2022 - 2024 乳歯歯髄幹細胞培養上清・エクソソームの骨誘導機序の解明と口蓋裂骨再生治療への応用
2020 - 2023 乳歯歯髄由来幹細胞培養上清の骨再生機構の解明と口蓋裂顎裂部骨再生治療への臨床応用

Papers (15)：

Rio Shibata, Ryo Kunimatsu, Shota Ito, Tomohiro Ogasawara, Shintaro Ogashira, Ayaka Nakatani, Kodai Rikitake, Ayaka Odo, Akira Hirabae, Io Koyanagi, et al. Role of Extracellular Vesicles of Stem Cells from Human Exfoliated Deciduous Teeth in Osteogenesis. International Journal of Molecular Sciences. 2025. 26. 12. 5841-5841
Kodai Rikitake, Ryo Kunimatsu, Yuki Yoshimi, Kengo Nakajima, Tomoka Hiraki, Nurul Aisyah Rizky Putranti, Yuji Tsuka, Takaharu Abe, Kazuyo Ando, Yoko Hayashi, et al. Effect of CD146(+) SHED on bone regeneration in a mouse calvaria defect model. Oral Diseases. 2023. 29. 2. 725-734
Ryo Kunimatsu, Tomoka Hiraki, Kodai Rikitake, Kengo Nakajima, Nurul Aisyah Rizky Putranti, Takaharu Abe, Kazuyo Ando, Ayaka Nakatani, Shuzo Sakata, Kotaro Tanimoto. Effects of Human Deciduous Dental Pulp-Derived Mesenchymal Stem Cell-Derived Conditioned Medium on the Metabolism of HUVECs, Osteoblasts, and BMSCs. Cells. 2022. 11. 20
Nurul Aisyah Rizky Putranti, Ryo Kunimatsu, Kodai Rikitake, Tomoka Hiraki, Kengo Nakajima, Takaharu Abe, Yuji Tsuka, Shuzo Sakata, Ayaka Nakatani, Hiroki Nikawa, et al. Combination of Carbonate Hydroxyapatite and Stem Cells from Human Deciduous Teeth Promotes Bone Regeneration by Enhancing BMP-2, VEGF and CD31 Expression in Immunodeficient Mice. Cells. 2022. 11. 12. 1914-1914
Yuji Tsuka, Ryo Kunimatsu, Hidemi Gunji, Takaharu Abe, Cynthia Concepción Medina, Tomoka Hiraki, Ayaka Nakatani, Shuzo Sakata, Kodai Rikitake, Purtranti Nurul Aisyah, et al. Examination of the effect of combined use of Er:YAG laser irradiation and mechanical force loading on bone metabolism using primary human gingival fibroblasts. Lasers in medical science. 2020. 35. 9. 2059-2064

ｍore...

MISC (1)：

中島健吾, 國松亮, 角明美, 粟田哲也, 阿部崇晴, 安藤和代, 柄優至, 平木智香, 加来真人, 谷本幸太郎. 乳歯歯髄由来間葉系幹細胞を用いた骨再生治療. 日本口蓋裂学会雑誌. 2017. 42. 2. 172-172

Lectures and oral presentations (12)：

Stem cell-derived conditioned media from human exfoliated deciduous teeth promotes bone regeneration
(The 12th Asian Pacific Orthodontic Congress, The 79th Annual Meeting of the Japanese Orthodontic Society (Yokohama),)
Success rates in isolating mesenchymal stem cells from permanent and deciduous teeth
(The 9th International Orthodontic Congress, The 12th Asian Pacific Orthodontic Congress, The 79th Annual Meeting of the Japanese Orthodontic Society (Yokohama))
Comparative characterization of stem cells from human exfoliated deciduous teeth, dental pulp, and bone marrow-derived mesenchymal stem cells
(The 9th International Orthodontic Congress, The 12th Asian Pacific Orthodontic Congress, The 79th Annual Meeting of the Japanese Orthodontic Society (Yokohama))
Effect of Nd:YAG laser irradiation and Mechanical force on cultured human osteoblasts
(The 9th International Orthodontic Congress, The 12th Asian Pacific Orthodontic Congress, The 79th Annual Meeting of the Japanese Orthodontic Society (Yokohama))
ヒト乳歯歯髄由来間葉系幹細胞、永久歯歯髄由来間葉系幹細胞および骨髄由来間葉系幹細胞における特性の比較
(第44回日本口蓋裂学会総会(名古屋))

ｍore...

Awards (3)：

2021/07 - 日本矯正歯科学会第24回日本矯正歯科学会学術奨励賞 Stem cell-derived conditioned media from human exfoliated deciduous teeth promotes bone regeneration
2019/11 - 第78回日本矯正歯科学会学術大会優秀演題発表賞乳歯歯髄由来間葉系幹細胞培養上清の骨再生治療への応用
2019/10 - Korean Association of Orthodontists Excellent Posterboard Presentation Award

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page