Rchr
J-GLOBAL ID：202001001377473925
Update date: Sep. 18, 2024
ABE JUNPEI
アベ ジュンペイ | ABE JUNPEI
Affiliation and department：
Other affiliations (1)：
Research field (3)：
Pharmaceuticals - chemistry and drug development
, Bioorganic chemistry
, Synthetic organic chemistry
Papers (10)：
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Junpei Abe, Yusaku Sasae, Yoichi Takeda, Takashi Kikuma, Yasuhiro Kajihara, Yukishige Ito. Society For Glycobiology 2023 Abstracts (Squaryl group-modified UDP Analogs as novel inhibitors of UDP-Glc:glycoprotein glucosyltransferase (UGGT)). Glycobiology. 2023. 33. 11. 954-1103
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Yanbo Liu, Kota Nomura, Junpei Abe, Yasuhiro Kajihara. Recent advances on the synthesis of N-linked glycoprotein for the elucidation of glycan functions. Current opinion in chemical biology. 2023. 73. 102263-102263
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Junpei Abe, Yoichi Takeda, Takashi Kikuma, Yasuhiko Kizuka, Hiroyuki Kajiura, Yasuhiro Kajihara, Yukishige Ito. Squaryl group-modified UDP analogs as inhibitors of the endoplasmic reticulum-resident folding sensor enzyme UGGT. Chemical Communications. 2023. 59. 2803-2806
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Adam T. Guy, Feiqing Ding, Junpei Abe, Mariko Inoue, Yoshio Hirabayashi, Yukishige Ito, Hiroyuki Kamiguchi, Peter Greimel. Lysolipid Chain Length Switches Agonistic to Antagonistic G Protein-Coupled Receptor Modulation. ACS Chemical Neuroscience. 2020. 11. 21. 3635-3645
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Junpei Abe, Adam T. Guy, Feiqing Ding, Peter Greimel, Yoshio Hirabayashi, Hiroyuki Kamiguchi, Yukishige Ito. Systematic synthesis of novel phosphoglycolipid analogues as potential agonists of GPR55. Organic & Biomolecular Chemistry. 2020. 18. 41. 8467-8473
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Lectures and oral presentations (30)：
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高活性 UGGT 阻害剤開発を指向したスクアリル基修飾型 UDP 類縁体とウラシル骨格修飾体 の合成研究
(2024)
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Regulation of THP-1 Cell Migration by GPR55 Inhibition of Squaryl-Group Modified Lysophosphatidyl-β-D-glucoside Analog
(2024)
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無保護硫酸基を有する新規糖供与体の開発とコンドロイチン硫酸合成への応用
(第43回日本糖質学会年会 2024)
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Pharmacological characterization of lyso-thiosquarylglucoside compounds as candidate non-competitive antagonists of G protein-coupled receptor GPR55
(NEURO2024)
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Squaryl group-modified lysophosphatidyl-β-D-glucoside analogs as GPR55 regulators
(2024)
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Professional career (1)：
- Ph.D. (The University of Tokyo, Grad. Sch. Pharm. Sci., Fac. Pharm. Sci.)
Work history (7)：
Awards (3)：
- 2024/09 - The Japanese Society of Carbohydrate Research Carbohydrate Research JSCR43 Poster Award Regulation of THP-1 cell migration by GPR55 inhibition of squaryl-group modified lysophosphatidyl-β-D-glucoside analog
- 2023/12 - The Society of Synthetic Organic Chemistry, Japan ダイセル研究企画賞
- 2018/11 - 10th Asian Community of Glycoscience and Glycotechnology Conference Poster Award Synthesis of squaryl group modified glycolipid analogs toward development of potent GPR55 agonists
Association Membership(s) (4)：
The Society of Synthetic Organic Chemistry
, The Chemical Society of Japan
, The Japanese Society of Carbohydrate Research
, 日本薬学会
