UMEHARA TAKASHI

ウメハラタカシ | UMEHARA TAKASHI

Affiliation and department：

Research field (1)： Animal production science

Research keywords (1)： Animal reproduction, Reproductive biology, Reproductive technology

Research theme for competitive and other funds (4)：

2023 - 2027 Study of the Mechanism of Ovarian Maturation Focusing on Gradual Cellular Composition Changes in the Strom
2023 - 2025 アンドロゲンを中心とした精漿産生機構の解明と,それを基盤とした人工精漿開発
2021 - 2023 Developing Treatment Strategies for Reproductive Disorders/Functional Disorders with a Focus on Novel Sensor Technologies and Ovarian Stromal Tissue
2019 - 2020 A study on the treatment of reproductive disorder focusing on ovarian fibrosis

Papers (9)：

Yamanaka, Takahiro, Xiao, Zimo, Tsujita, Natsumi, Awad, Mahmoud, Umehara, Takashi, Shimada, Masayuki. Testosterone-induced metabolic changes in seminal vesicle epithelium modify seminal plasma components with potential to improve sperm motility. ELIFE. 2025. 13
Njoroge, Wambugu Enoc, Zhu, Zhendong, Umehara, Takashi, Yamanaka, Takahiro, Zeng, Wenxian, Okazaki, Tetsuji, Shimada, Masayuki. Synthesis of functional enzymes involved in glutathione production during linear motility in boar sperm. FREE RADICAL BIOLOGY AND MEDICINE. 2025. 228. 126-136
Umehara, Takashi, Yamanaka, Takahiro, Shimada, Masayuki. Toll-like receptors in mammalian sperm. REPRODUCTIVE MEDICINE AND BIOLOGY. 2025. 24. 1
Winstanley, Yasmyn E., Stables, Jennifer S., Gonzalez, Macarena B., Umehara, Takashi, Norman, Robert J., Robker, Rebecca L. Emerging therapeutic strategies to mitigate female and male reproductive aging. NATURE AGING. 2024. 4. 12. 1682-1696
Morimoto, Atsushi, Rose, Ryan D., Smith, Kirsten M., Dinh, Doan T., Umehara, Takashi, Winstanley, Yasmyn E., Shibahara, Hiroaki, Russell, Darryl L., Robker, Rebecca L. Granulosa cell metabolism at ovulation correlates with oocyte competence and is disrupted by obesity and aging. HUMAN REPRODUCTION. 2024. 39. 9

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Patents (2)：

Books (2)：

Lectures and oral presentations (5)：

TLR7/8 依存的な卵丘細胞のサイトカインストームが受精障害を誘発する
(第65回日本卵子学会学術集会 2024)
食事誘発性肥満モデルマウスにおける雄妊孕性の経時的変化
(第28回日本生殖内分泌学会 2023)
マウス顆粒膜細胞における脂質代謝が卵胞発育・排卵・黄体化へ与える影響
(第41回日本受精着床学会総会・学術集会 2023)
精巣老化の真実 ~ライディッヒ細胞の代謝機能低下が引き起こす影響
(第22回日本抗加齢医学会総会 2022)
ミトコンドリアに着眼した加齢や肥満に伴う卵巣線維化メカニズムと代謝改善によるその治療法の構築
(第23回日本IVF学会 2020)

Education (3)：

Professional career (2)：

Work history (5)：

2024/04/01 - Hiroshima University Graduate School of Integrated Sciences for Life Associate Professor
2019/04/01 - 2024/03/31 Hiroshima university Graduate School of Integrated Sciences for Life Assistant professor
2019/09/02 - 2020/09/11 Robinson Research Institute; The University of Adelaide Robinson Research Institute Visiting research fellow
2018/04/01 - 2019/03/31 Hiroshima University Global Career Design Center Special Postdoctral Researcher
2015/04/01 - 2018/03/31 Japan Society for the Promotion of Science Research Fellowships for Young Scientists, DC1

Awards (8)：

2023/07/28 - 一般社団法人日本受精着床学会理事長世界体外受精会議記念賞(基礎) 精嚢腺上皮細胞における代謝関連遺伝子群の発現変動が,精子の受精能を向上させる
2022/11/03 - 一般社団法人日本生殖医学会 RMB優秀論文賞 Saturated fatty acids accelerate linear motility through mitochondrial ATP production in bull sperm
2022/09/15 - 公益社団法人日本畜産学会日本畜産学会奨励賞 ATP合成とその効率的利用機構に着眼したブタ精子運動,受精機構の解析
2021/11/11 - 一般社団法人日本生殖医学会理事長日本生殖医学会RMB優秀論文賞 Cutting the ovarian surface improves the responsiveness to exogenous hormonal treatment in aged mice
2020/12/03 - 一般社団法人日本生殖医学会理事長日本生殖医学会学術奨励賞 X染色体をもつ精子にのみToll様受容体7/8が発現し,その制御によって簡便な雌雄産み分けが可能になる

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Association Membership(s) (3)：

Japan Society for Reproductive Medicine , Japan Society of Fertilization and Implantation , Japan Society for Ova Research

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