Rchr
J-GLOBAL ID:202001002532560518   Update date: Feb. 23, 2022

Kawaguchi Daichi

カワグチ ダイチ | Kawaguchi Daichi
Affiliation and department:
Job title: 助教
Research field  (2): Neuroscience - general ,  Developmental biology
Research keywords  (5): 脳・神経 ,  ニューロン ,  神経幹細胞 ,  大脳皮質 ,  神経発生
Research theme for competitive and other funds  (5):
  • 2021 - 2024 自閉症の病態理解に向けた神経幹細胞運命制御メカニズムの解明
  • 2018 - 2021 自閉症早期にみられる領域特異的な大脳新皮質肥大のメカニズムの解明
  • 2016 - 2018 Molecular mechanisms of neocortical malformation relevant to autism spectrum disorder
  • 2009 - 2010 Regulatory mechanism of neural stem cell maintenance in the embryonic and adult brain
  • 2006 - 2008 マウス大脳皮質発生におけるNotch-Delta経路の機能解析
Papers (17):
  • Yujin Harada, Mayumi Yamada, Itaru Imayoshi, Ryoichiro Kageyama, Yutaka Suzuki, Takaaki Kuniya, Shohei Furutachi, Daichi Kawaguchi, Yukiko Gotoh. Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module. Nature communications. 2021. 12. 1. 6562-6562
  • Shun Utsunomiya, Yusuke Kishi, Masafumi Tsuboi, Daichi Kawaguchi, Yukiko Gotoh, Manabu Abe, Kenji Sakimura, Kazuma Maeda, Hiroshi Takemoto. Ezh1 regulates expression of Cpg15/Neuritin in mouse cortical neurons. Drug discoveries & therapeutics. 2021. 15. 2. 55-65
  • Naoya Yuizumi, Yujin Harada, Takaaki Kuniya, Takehiko Sunabori, Masato Koike, Masaki Wakabayashi, Yasushi Ishihama, Yutaka Suzuki, Daichi Kawaguchi, Yukiko Gotoh. Maintenance of neural stem-progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Stem cells (Dayton, Ohio). 2021
  • Hanae Omiya, Shima Yamaguchi, Tomoyuki Watanabe, Takaaki Kuniya, Yujin Harada, Daichi Kawaguchi, Yukiko Gotoh. BMP signaling suppresses Gemc1 expression and ependymal differentiation of mouse telencephalic progenitors. Scientific reports. 2021. 11. 1. 613-613
  • Yui Imaizumi, Shohei Furutachi, Tomoyuki Watanabe, Hiroaki Miya, Daichi Kawaguchi, Yukiko Gotoh. Role of the imprinted allele of the Cdkn1c gene in mouse neocortical development. Scientific reports. 2020. 10. 1. 1884-1884
more...
MISC (4):
  • 後藤 昂宏, 表 伯俊, 川口 大地. 【脳の半分を占めるグリア細胞 脳と心と体をつなぐ"膠"】(第1章)グリア細胞の分化・神経発達 神経系前駆細胞(放射状グリア)とアストロサイトの多様性. 実験医学. 2019. 37. 17. 2822-2827
  • 今泉 結, 川口 大地, 古舘 昌平, 後藤 由季子. 成体神経幹細胞の未分化性維持機構と発生起源について. 生化学. 2016. 88. 6. 766-770
  • 川口 大地, 古舘 昌平, 後藤 由季子. 成体神経幹細胞の枯渇を防ぐための幹細胞ストラテジー. 細胞工学. 2014. 33. 3. 310-315
  • 川口 大地, 後藤 由季子. 【幹細胞研究の最近の進歩 多能性幹細胞】幹細胞の臨床応用 神経幹細胞の運命制御にかかわるシグナル伝達. 最新医学. 2009. 64. 6月増刊. 1417-1425
Education (2):
  • - 2009 The University of Tokyo Department of Integrated Biosciences
  • - 2004 The University of Tokyo Department of Chemistry and Biotechnology
Professional career (1):
  • 博士(生命科学) (東京大学)
Work history (5):
  • 2016/01 - 現在 The University of Tokyo Graduate School of Pharmaceutical Sciences
  • 2011/01 - 2015/12 The Salk Institute Molecular Neurobiology Laboratory
  • 2010/04 - 2011/01 The University of Tokyo Institute of Molecular and Cellular Biosciences
  • 2009/04 - 2010/03 The University of Tokyo Institute of Molecular and Cellular Biosciences
  • 2006/04 - 2009/03 日本学術振興会 特別研究員(DC1)
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