INAGAKI EMI

イナガキエミ | INAGAKI EMI

Affiliation and department：
Job title： Project Assistant Professor
Research theme for competitive and other funds (5)：

2021 - 2023 間葉系幹細胞局所投与による眼表面難治疾患制御法の開発
2020 - 2023 健康長寿をめざしたin vitro認知症研究基盤の開発と概日リズム制御機構の解明
2019 - 2021 A New Anterior Chamber Transplantation Model of In Vivo Tumoriogenicity Test Towards iPSC Derived Cell Treatment
2017 - 2020 A novel prevention and treatment method of ocular aging by targeting sirtuins.
2016 - 2019 角膜内皮細胞機能制御におけるNAD+の生理学的重要性と治療標的としての可能性

Papers (32)：

Masatoshi Hirayama, Shin Hatou, Masaki Nomura, Risa Hokama, Osama Ibrahim Hirayama, Emi Inagaki, Kumi Aso, Tomoko Sayano, Hiromi Dohi, Tadaaki Hanatani, et al. A first-in-human clinical study of an allogenic iPSC-derived corneal endothelial cell substitute transplantation for bullous keratopathy. Cell reports. Medicine. 2025. 6. 1. 101847-101847
Robert M Rusch, Emi Inagaki, Hiroko Taniguchi, Saki Sakakura, Rie Tamai, Hidenori Nonaka, Shota Shimizu, Shinri Sato, Yoko Ogawa, Hirayama Masatoshi, et al. Adipose-derived mesenchymal stromal cells: A study on safety and efficacy in ocular inflammation. The ocular surface. 2024. 34. 523-534
Shigeto Shimmura, Emi Inagaki, Masatoshi Hirayama, Shin Hatou. The Cornea: An Ideal Tissue for Regenerative Medicine. The Keio journal of medicine. 2024. 73. 1. 1-7
Shintaro Yamaguchi, Junichiro Irie, Masanori Mitsuishi, Yuichi Uchino, Hideaki Nakaya, Ryo Takemura, Emi Inagaki, Shotaro Kosugi, Hideyuki Okano, Masato Yasui, et al. Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japanese men. Endocrine journal. 2024. 71. 2. 153-169
Saki Sakakura, Emi Inagaki, Tomoko Sayano, Risa Yamazaki, Noemi Fusaki, Shin Hatou, Masatoshi Hirayama, Kazuo Tsubota, Kazuno Negishi, Hideyuki Okano, et al. Non-apoptotic regulated cell death in Fuchs endothelial corneal dystrophy. Regenerative therapy. 2023. 24. 592-601

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MISC (11)：

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Patents (6)：

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Lectures and oral presentations (25)：

NAD-related metabolites attenuate the phenotype of corneal endothelial cells derived from Fuchs corneal endothelial degeneration patioents derived-iPS cells
(International Society for Stem Cell Research (ISSCR) 2022)
Best Presentation Award Lecture; Possibility of disease control by nutritional approach using NAD-related metabolites - using iPS cells derived from patients with Fuchs' corneal endothelial degeneration
(The 22nd Annual Meeting of the Japanese Society of Anti-Aging Medicine 2022)
Symposium 3; "Frontiers of Basic Corneal Research for the Developoment of Novel Therapies", Application of iPSC derived corneal endothelial cells for disease modeling
(The 126th Annual Meeting of the Japanese Ophthalmological Society 2022)
NAD regulates key metabolic functions in iPSC derived neurons
(International Society for Stem Cell Research (ISSCR) 2021 2021)
Transplantation of iPS derived corneal endothelial substitutes in a monkey bullous keratopathy model
(International Society for Stem Cell Research (ISSCR) 2021 2021)

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Education (2)：

2023 - 2024 Keio University Graduate School of Health Management Master of Public Health
2011 - 2015 Keio University Graduate School of Medicine

Awards (15)：

2023/05 - Japan Medical women's Association Michiko Yamazaki Award
2023/03 - Outstanding presentation award AMED Interstellar initiative/ New York Academy of Science
2023/02 - The 47th Japan Cornea Society Promising Investigator Award
2022/09 - The Maureen and Mike Mansfield Foundation Cohort8 scholar Pharmaceutical Research and Manufacturers of America
2022/09 - The 28th Kyoto Cornea Society Kyoto Cornea Award

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