Kohashi Kenichi

コウハシケンイチ | Kohashi Kenichi

Research theme for competitive and other funds (21)：

2023 - 2027 空間的マルチオミクス解析による軟部肉腫の腫瘍微小環境の解明と代謝標的治療法の探索
2023 - 2027 空間的マルチオミクス解析による軟部肉腫の腫瘍微小環境の解明と代謝標的治療法の探索
2021 - 2026 乳歯歯髄幹細胞によるヒルシュスプルング病と類縁疾患の病因解明および根治療法の開発
2021 - 2024 SWI/SNF型クロマチン再構成因子関連腫瘍の分子生物学的層別化と治療戦略
2021 - 2024 腸管運動機能不全における形態学的特徴の解明および新しい診断基準の開発に関する研究

2020 - 2023 小児固形悪性腫瘍に対する超音波硬度計測における組織硬度と病理学的分子生物学的解析

2020 - 2023 Quantification of right ventricular fibrosis with cardiac magnetic resonance imaging and dual-energy computed tomography

2019 - 2023 Multi-omics analysis of the mechanisms of tumorigenesis and acquired treatment resistance in rare cancer, sarcoma

2017 - 2021 Evaluation of FOXM1 and major signaling pathways as target molecule in pediatric malignant soft tissue tumor

2017 - 2020 MTH1 expression in pediatric malignant solid tumor: a new therapeutic target

2017 - 2020 SWI/SNF chromatin-remodeling complex status in tumors with sarcomatoid changes

2016 - 2020 Elucidation of the etiology and development of the novel therapy using stem cells from human exfoliated deciduous teeth for Hirschsprung's disease and its allied disorders

2015 - 2018 Development of the methods to fabricate a macro-scale liver tissue containinf the bile duct usgin 3D bioprinter

2014 - 2017 Evaluation of FOXM1 and related protein expression as target molecule in refractory pediatric malignant soft tissue tumor

2014 - 2017 SWI/SNF chromatin remodeling complex status in soft tissue tumors

2013 - 2017 Global search for molecular target in translocation associated and non-translocation associated soft tissue sarcoma

2012 - 2015 The development of new molecular target treatment drug for neuroblastoma using MYCN transgenic mouse

2012 - 2015 Development of new therapy for congenital metabolic disorders using functional three-dimensional liver structures constructed by stem cells from human exfoliated deciduous teeth

2012 - 2014 Re-classification for therapeutic application in SMARCB1/INI1 deficient tumors

2009 - 2012 Analysis of the alteration of signal pathway in soft tissue sarcoma

2009 - 2011 Molecular-biological analysis and differential diagnosis in epithelioid sarcoma and malignant rhabdoid tumor

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Papers (401)：

K. Kawaguchi, M. Endo, E. Shimada, K. Kohashi, T. Hirose, A. Nabeshima, T. Fujiwara, A. Kawai, Y. Oda, Y. Nakashima. Translocation in bone and soft tissue sarcomas: a comprehensive epidemiological investigation. ESMO Open. 2024. 9. 10. 103726
Daisuke Kiyozawa, Takeshi Iwasaki, Dai Takamatsu, Kenichi Kohashi, Takumi Miyamoto, Genshiro Fukuchi, Masatoshi Eto, Michifumi Yamashita, Yoshinao Oda. Papillary renal neoplasm with reverse polarity has low frequency of alterations in chromosomes 7, 17, and Y. Virchows Archiv : an international journal of pathology. 2024. 485. 2. 299-306
Yuichi Shibui, Kenichi Kohashi, Yuko Hino, Akihiko Tamaki, Izumi Kinoshita, Hidetaka Yamamoto, Yasuharu Nakashima, Tatsuro Tajiri, Yoshinao Oda. Expression of Forkhead Box M1 and Anticancer Effects of FOXM1 Inhibition in Epithelioid Sarcoma. Laboratory investigation; a journal of technical methods and pathology. 2024. 104. 8. 102093-102093
Masaki Naka, Hidetaka Yamamoto, Kenichi Kohashi, Takeshi Iwasaki, Taro Mori, Miwako Nogami, Fumihiko Ookubo, Kayoko Higuchi, Toru Motoi, Yoshinao Oda. Reappraisal of bone and soft tissue cytopathology classification using the modified Milan system. Cancer cytopathology. 2024
Kengo Kawaguchi, Kenichi Kohashi, Takeshi Iwasaki, Taro Mori, Hiroshi Furukawa, Chiaki Sato, Hiroki Sonoda, Sakura Shiraishi, Makoto Endo, Yasuharu Nakashima, et al. Nuclear morphological atypia in biopsy accurately reflects the prognosis of myxoid liposarcoma. Virchows Archiv : an international journal of pathology. 2024

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MISC (63)：

川床慎一郎, 川崎啓祐, 水江龍太郎, 孝橋賢一, 鳥巣剛弘, 北園孝成. 遺伝子解析を行った直腸の腺腫と腺癌の衝突腫瘍の1例. 日本消化器病学会九州支部例会・日本消化器内視鏡学会九州支部例会プログラム・抄録集. 2022. 120回・114回. 205-205
川床慎一郎, 孝橋賢一, 佐々木泰介, 鳥巣剛弘, 北園孝成, 小田義直. 胃充実型低分化腺癌におけるPD-L1,IDO1の発現と腫瘍浸潤リンパ球についての検討(PD-L1/IDO1 expression and TIL in solid-type poorly differentiated gastric adenocarcinoma (Solid-PDA)). 日本病理学会会誌. 2022. 111. 1. 226-226
川床慎一郎, 孝橋賢一, 佐々木泰介, 鳥巣剛弘, 北園孝成, 小田義直. 胃充実型低分化腺癌におけるPD-L1,IDO1の発現と腫瘍浸潤リンパ球についての検討(PD-L1/IDO1 expression and TIL in solid-type poorly differentiated gastric adenocarcinoma (Solid-PDA)). 日本病理学会会誌. 2022. 111. 1. 226-226
川床慎一郎, 孝橋賢一, 長末智寛, 鳥巣剛弘, 北園孝成. 特異な形態を呈した胃充実型低分化腺癌に対する分子病理学的考察. 日本消化器病学会九州支部例会・日本消化器内視鏡学会九州支部例会プログラム・抄録集. 2021. 118回・112回. 167-167
伊東良広, 孝橋賢一, 山田裕一, 薄陽祐, 川口健悟, 木下伊寿美, 遠藤誠, 山元英崇, 中島康晴, 小田義直. MPNSTにおけるH3K27me3およびH3K27me2発現臨床病理学的特徴と免疫染色との関連性. 日本病理学会会誌. 2021. 110. 1. 233-233

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Association Membership(s) (4)：

日本小児血液・がん学会 , 日本癌学会 , 日本臨床細胞学会 , 日本病理学会

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